205864-92-2

Upstream product

• 221381-13-1 5-benzyloxy-2-{3-[5-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-[1,3]dioxan-4-yl]-propenyl}-7-[3-(tert-butyl-diphenyl-silanyloxy)-propyl]-3,3-bis-ethylsulfanyl-decahydro-1,8,10-trioxa-anthracene 
• 221381-14-2 C₅₁H₈₄O₉Si₃ 
• 205865-14-1 (2R,4S,5R)-4-((Z)-3-{(2R,4aR,5S,7R,8aR,9aS,10aS)-5-Benzyloxy-7-[3-(tert-butyl-diphenyl-silanyloxy)-propyl]-3,3-bis-ethylsulfanyl-decahydro-1,8,10-trioxa-anthracen-2-yl}-allyl)-2-phenyl-[1,3]dioxan-5-ol 
• 221381-15-3 C₄₉H₈₂O₈Si₃ 
• 221381-16-4 C₄₉H₈₀O₈Si₃ 
• 221380-99-0 {(2S,3S)-3-[(2R,3S,4aR,6S,8S,8aS)-8-Benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxymethyl)-octahydro-pyrano[3,2-b]pyran-2-ylmethyl]-oxiranyl}-methanol 
• 221380-97-8 (E)-4-[(2R,3S,4aR,6S,8S,8aS)-8-Benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxymethyl)-octahydro-pyrano[3,2-b]pyran-2-yl]-but-2-enoic acid methyl ester 
• 221380-98-9 (E)-4-[(2R,3S,4aR,6S,8S,8aS)-8-Benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxymethyl)-octahydro-pyrano[3,2-b]pyran-2-yl]-but-2-en-1-ol 
• 221381-01-7 (2R,3S,4aR,6S,8S,8aS)-8-Benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxymethyl)-2-((2S,3S)-3-vinyl-oxiranylmethyl)-octahydro-pyrano[3,2-b]pyran 
• 221381-00-6 (2R,3S)-3-[(2R,3S,4aR,6S,8S,8aS)-8-Benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxymethyl)-octahydro-pyrano[3,2-b]pyran-2-ylmethyl]-oxirane-2-carbaldehyde 
• 221381-12-0 [3-((4aR,5aS,6aR,8R,10S,10aS,11aR,12aS)-10-Benzyloxy-2,2-dimethyl-dodecahydro-1,3,5,7,11-pentaoxa-naphthacen-8-yl)-propoxy]-tert-butyl-diphenyl-silane 
• 221380-91-2 {(2S,3S)-3-[(2R,3S,4S,6S)-4-Benzyloxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-triethylsilanyloxy-tetrahydro-pyran-2-ylmethyl]-oxiranyl}-methanol 
• 221380-95-6 2-[(2R,3S,4aR,6S,8S,8aS)-8-Benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxymethyl)-octahydro-pyrano[3,2-b]pyran-2-yl]-ethanol 
• 221381-06-2 ((4aR,5aS,6aR,8S,10S,10aS,11aR,12aS)-10-Benzyloxy-2,2-dimethyl-dodecahydro-1,3,5,7,11-pentaoxa-naphthacen-8-ylmethoxy)-tert-butyl-diphenyl-silane 

Relevant academic research and scientific papers

Total synthesis of brevetoxin A: Part 3: Construction of GHIJ and BCDE ring systems

Successful syntheses of highly complex intermediates 2 (GHIJ ring system) and 3 (BCDE ring system) for the total synthesis of brevetoxin A (1) are described. Several of our methodologies were utilized to achieve this goal: i) hydroxy epoxide cyclizations