205865-31-2

Upstream product

• 933-40-4 cycloxexanone dimethyl ketal 
• 205865-30-1 (2S,3R,4S,5aS,6aR,8R,10S,11R,12aS,13aR)-10-(tert-Butyl-diphenyl-silanyloxy)-2,11-bis-(2-hydroxy-ethyl)-4,6a,8-trimethyl-tetradecahydro-1,6,12-trioxa-cyclohepta[4,5]benzo[1,2]cycloocten-3-ol 
• 126694-06-2 (2S,3R,4S,5aS,6aR,8R,10S,11R,12aS,13aR)-2,11-Bis-(2-benzyloxy-ethyl)-10-(tert-butyl-diphenyl-silanyloxy)-4,6a,8-trimethyl-tetradecahydro-1,6,12-trioxa-cyclohepta[4,5]benzo[1,2]cycloocten-3-ol 

Downstream Products

• 205865-04-9 C₄₈H₇₂O₈Si 
• 205865-34-5 2,2-Dimethyl-propionic acid 2-[(2S,3R,4S,5aS,6aR,8R,10S,11R,12aS,13aR)-3-acetoxy-10-(tert-butyl-diphenyl-silanyloxy)-4,6a,8-trimethyl-2-(2-trityloxy-ethyl)-tetradecahydro-1,6,12-trioxa-cyclohepta[4,5]benzo[1,2]cycloocten-11-yl]-ethyl ester 
• 205865-33-4 2,2-Dimethyl-propionic acid 2-[(2S,3R,4S,5aS,6aR,8R,10S,11R,12aS,13aR)-10-(tert-butyl-diphenyl-silanyloxy)-3-hydroxy-4,6a,8-trimethyl-2-(2-trityloxy-ethyl)-tetradecahydro-1,6,12-trioxa-cyclohepta[4,5]benzo[1,2]cycloocten-11-yl]-ethyl ester 
• 205865-36-7 (Z)-6-{(2S,3R,4S,5aS,6aR,8R,10S,11R,12aS,13aR)-3-Acetoxy-10-(tert-butyl-diphenyl-silanyloxy)-11-[2-(2,2-dimethyl-propionyloxy)-ethyl]-4,6a,8-trimethyl-tetradecahydro-1,6,12-trioxa-cyclohepta[4,5]benzo[1,2]cycloocten-2-yl}-hex-4-enoic acid methyl ester 
• 205865-06-1 (Z)-6-{(2S,3R,4S,5aS,6aR,8R,10S,11R,12aS,13aR)-10-(tert-Butyl-diphenyl-silanyloxy)-11-[2-(2,2-dimethyl-propionyloxy)-ethyl]-3-hydroxy-4,6a,8-trimethyl-tetradecahydro-1,6,12-trioxa-cyclohepta[4,5]benzo[1,2]cycloocten-2-yl}-hex-4-enoic acid 
• 221380-85-4 C₄₆H₆₆O₈Si 
• 205865-05-0 2,2-Dimethyl-propionic acid 2-[(2S,3R,4S,5aS,6aR,8R,10S,11R,12aS,13aR)-3-acetoxy-10-(tert-butyl-diphenyl-silanyloxy)-2-(2-hydroxy-ethyl)-4,6a,8-trimethyl-tetradecahydro-1,6,12-trioxa-cyclohepta[4,5]benzo[1,2]cycloocten-11-yl]-ethyl ester 
• 205865-32-3 2,2-Dimethyl-propionic acid 2-[(2S,3R,4S,5aS,6aR,8R,10S,11R,12aS,13aR)-10-(tert-butyl-diphenyl-silanyloxy)-3-hydroxy-2-(2-hydroxy-ethyl)-4,6a,8-trimethyl-tetradecahydro-1,6,12-trioxa-cyclohepta[4,5]benzo[1,2]cycloocten-11-yl]-ethyl ester 
• 205865-35-6 2,2-Dimethyl-propionic acid 2-[(2S,3R,4S,5aS,6aR,8R,10S,11R,12aS,13aR)-3-acetoxy-10-(tert-butyl-diphenyl-silanyloxy)-4,6a,8-trimethyl-2-(2-oxo-ethyl)-tetradecahydro-1,6,12-trioxa-cyclohepta[4,5]benzo[1,2]cycloocten-11-yl]-ethyl ester 

Relevant academic research and scientific papers

Total synthesis of brevetoxin A: Part 3: Construction of GHIJ and BCDE ring systems

Successful syntheses of highly complex intermediates 2 (GHIJ ring system) and 3 (BCDE ring system) for the total synthesis of brevetoxin A (1) are described. Several of our methodologies were utilized to achieve this goal: i) hydroxy epoxide cyclizations