20587-30-8

Basic information

• Product Name: Methyl 5-Methyl-2-Nitrobenzoate
• Synonyms: Methyl 5-Methyl-2-Nitrobenzoate;2-(Ethoxycarbonyl)-4-methylnitrobenzene, 3-(Ethoxycarbonyl)-4-nitrotoluene;5-Methyl-2-nitrobenzoic acid methyl ester;Methyl 6-nitro-m-toluate;5-Methyl-2-Nitrobenzoate Methyl;2-(Methoxycarbonyl)-4-methylnitrobenzene, 3-(Methoxycarbonyl)-4-nitrotoluene;5-methyl-2-nitrobenzoic acid methyl ester 90%
• CAS NO: 20587-30-8
• Molecular Formula: C₉H₉NO₄
• Molecular Weight: 195
• Mol File: 20587-30-8.mol
• Article Data: 12

Chemical Properties

• Melting Point: 77-79℃
• Boiling Point: 305.1±22.0 °C(Predicted)
• Appearance: /
• Density: 1.255
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• CAS DataBase Reference: Methyl 5-Methyl-2-Nitrobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 5-Methyl-2-Nitrobenzoate(20587-30-8)
• EPA Substance Registry System: Methyl 5-Methyl-2-Nitrobenzoate(20587-30-8)

Safety Data

• Hazardous Substances Data: 20587-30-8(Hazardous Substances Data)

Usage

General Description

Methyl 5-Methyl-2-Nitrobenzoate is a chemical compound with the molecular formula C9H9NO4. It is a yellow crystalline solid that is commonly used in the production of pharmaceuticals, dyes, and other organic compounds. The compound is a nitrobenzoate ester, which means it contains a nitro group (-NO2) and a methyl ester group (-COOCH3) attached to a benzene ring. Methyl 5-Methyl-2-Nitrobenzoate is primarily used as an intermediate in the synthesis of various organic compounds, and its properties make it suitable for a wide range of chemical reactions and applications. However, it is important to handle this compound with care, as it may pose health hazards if not properly managed.

Upstream product

• 99-36-5 1-methoxycarbonyl-3-methylbenzene 
• 7697-37-2 nitric acid 
• 99-04-7 m-Toluic acid 
• 3113-72-2 5-methyl-2-nitrobenzoic acid 
• 74-88-4 methyl iodide 
• 67-56-1 methanol 

Downstream Products

• 34161-82-5 2-methoxycarbonyl-4-methyl-N-(p-toluenesulfonyl)aniline 
• 1118507-77-9 7-methyl-1-toluenesulfonyl-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine 
• 1118507-72-4 7-methyl-1-toluenesulfonyl-2,3,4,5-tetrahydro-1H-1-benzazepine 

Relevant articles and documents

Discovery and Structure-Activity Relationships of Quinazolinone-2-carboxamide Derivatives as Novel Orally Efficacious Antimalarials

A phenotypic high-throughput screen allowed discovery of quinazolinone-2-carboxamide derivatives as a novel antimalarial scaffold. Structure-activity relationship studies led to identification of a potent inhibitor 19f, 95-fold more potent than the origin

Anti-inflammatory agents

Disclosed are novel compounds that are useful in regulating the expression of interleukin-6 (IL-6) and/or vascular cell adhesion molecule-1 (VCAM-1), and their use in the treatment and/or prevention of cardiovascular and inflammatory diseases and related disease states, such as, for example, atherosclerosis, asthma, arthritis, cancer, multiple sclerosis, psoriasis, and inflammatory bowel diseases, and autoimmune disease(s). Also, disclosed are compositions comprising the novel compounds, as well as methods for their preparation.

Synthetic approaches to natural antioxidant benzastatin E, F and G analogues

For synthesis of benzastatin E, F and G analogues, the indole-2- carbaldehydes with or without substituents at C-5 position were prepared as key intermediates. Several synthetic attempts to achieve benzastatin E-G analogues were suggested using the indole-2-carbaldehyde intermediates.