20595-52-2

Usage

Uses

Used in Pharmaceutical Synthesis:
(Z)-3-(3,4-Dichlorophenyl)propenoic acid is used as an intermediate in the pharmaceutical industry for the synthesis of various drugs and research chemicals. Its unique chemical properties allow for the creation of a wide range of compounds with potential therapeutic applications.
Used in Anti-Inflammatory and Analgesic Applications:
In the medical field, (Z)-3-(3,4-Dichlorophenyl)propenoic acid is used as a potential candidate for the development of anti-inflammatory and analgesic drugs. Some studies have shown that it exhibits these properties, making it a valuable compound for further research and development in the treatment of pain and inflammation.
Used in Chemical Research:
(Z)-3-(3,4-Dichlorophenyl)propenoic acid is also used as a research chemical, providing scientists with a valuable tool for studying various chemical reactions and processes. Its unique properties and reactivity make it an important compound in the field of chemical research.

Upstream product

• 7312-27-8 3,4-Dichlorocinnamic acid 
• 19498-74-9 3-(3,4-dichlorophenyl)prop-2-ynoic acid 
• 6287-38-3 3,4-dichlorobenzaldehyde 
• 110-16-7 maleic acid 
• 95-76-1 m,p-dichloroaniline 

Downstream Products

• 1075623-26-5 (2Z,2'Z)-N,N'-pentane-1,5-diylbis[3-(3,4-dichlorophenyl)acrylamide] 
• 7312-27-8 3,4-Dichlorocinnamic acid 

Relevant academic research and scientific papers

Template-stereocontrolled [2 + 2] photoreactions directed by surface recognition on hydrophilic functionalized carbon materials

Supramolecular assistance of the regioselective synthesis of single dimers from [2 + 2] photoreactions surface-directed by multivalent H-bonding exo-templates based on hydrophilic carbon materials (HCMs) is highlighted for the first time. Supramolecular p

Synthesis and pharmacological evaluation of bis-3-(3,4-dichlorophenyl)acrylamide derivatives as glycogen phosphorylase inhibitors

During our research using a high-throughput screening system for discovery of a new class of human liver glycogen phosphorylase a (hLGPa) inhibitors, a series of 3-(3,4-dichlorophenyl)acrylamide derivatives were synthesized, and their inhibitory activities toward hLGPa were evaluated. Among the derivatives, (2E,2′E)-N,N′-pentane-1,5-diylbis[3-(3,4-dichlorophenyl)acrylamide] (6c) inhibited hLGPa with an IC50 value of 0.023 μM. An X-ray crystallographic study of the enzyme-6c complex showed that the inhibitor is bound at the dimer interface site, where the 3,4-dichlorophenyl moiety interacts hydrophobically with the enzyme.