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205989-96-4

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205989-96-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 205989-96-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,5,9,8 and 9 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 205989-96:
(8*2)+(7*0)+(6*5)+(5*9)+(4*8)+(3*9)+(2*9)+(1*6)=174
174 % 10 = 4
So 205989-96-4 is a valid CAS Registry Number.

205989-96-4Relevant articles and documents

Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists

McDonald, Iain M.,Austin, Carol,Buck, Ildiko M.,Dunstone, David J.,Gaffen, John,Griffin, Eric,Harper, Elaine A.,Hull, Robert A. D.,Kalindjian, S. Barret,Linney, Ian D.,Low, Caroline M. R.,Patel, Dipa,Pether, Michael J.,Raynor, Michelle,Roberts, Sonia P.,Shaxted, Mark E.,Spencer, John,Steel, Katherine I. M.,Sykes, David A.,Wright, Paul T.,Xun, Wei

, p. 4789 - 4792 (2008/03/13)

A 1,3,4-benzotriazepine was identified as a suitable lead in our effort toward obtaining a non-peptide parathyroid hormone-1 receptor (PTH1R) antagonist. A process of optimization afforded derivatives displaying nanomolar PTH1R affinity, a representative example of which behaved as a PTH1R antagonist in cell-based cyclic adenosine monophosphate (cAMP) assays, with selectivity over PTH2 receptors.

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