206009-45-2

Upstream product

• 108-86-1 bromobenzene 
• 612-81-7 2,3'-biquinoline 
• 74-88-4 methyl iodide 
• 591-51-5 phenyllithium 
• 75380-86-8 1-methyl-3-(2-quinolyl)quinolinium iodide 
• 206009-40-7 4'-phenyl-1',4'-dihydro-2,3'-biquinoline 
• 77-78-1 dimethyl sulfate 

Relevant academic research and scientific papers

Studies of 2,3′-biquinolyl. 6. Regioselectivity of nucleophilic addition of organometallic compounds to 1-aklyl-3-(2-quinolyl)quinolinium halides

Nucleophilic addition of organometallic lithium and magnesium compounds to 1-alkyl-3-(2-quinolyl)quinolinium cations produces a mixture of the corresponding 1′-alkyl-2′-R-1′,2′-dihydro-2,3′-biquinolyls and 1′-alkyl-4′-R-1′,4′-dihydro-2,3′-biquinolyls. The

Investigations of 2,3′-biquinolyl. 8. Reduction of 1-alkyl-3-(2-quinolyl)quinolinium halides with sodium borohydride

Reduction of 1-alkyl-3-(2-quinolyl)quinolinium halides with sodium borohydride leads to 1′-alkyl-1′,2′-dihydro-2,3′-biquinolyls which, except for the ethoxycarbonyl derivative, undergo rearrangement to 1′-alkyl-1′,4′-dihydro-2,3′-biquinolyls. The last can

Investigation of 2,3′-biquinolyl. 10. The regioselectivity of the reaction of 2,3′-biquinolyl and 1′-alkyl-3-(2-quinolyl)quinolinium halides with halo derivatives in the presence of metallic lithium and magnesium

2,3′-Biquinolyl reacts with halo derivatives in the presence of metallic lithium to give addition products at position 4′, treatment of which with water gives 4′-R-1′,4′-dihydro-2,3′-biquinolyls and with halo derivatives gives 1′-alkyl-4′-R-1′,4′-dihydro-2,3′-biquinolyls. The reaction of 2,3′-biquinolyl with halo derivatives in the presence of metallic magnesium gives a mixture of products of addition at positions 2′ and 4′. 1-Alkyl-3-(2-quinolyl)quinolinium halides and halo derivatives with metallic magnesium give 1′-alkyl-2′-R-1′,2′-dihydro-2,3′-biquinolyls but form a complex mixture of substances when metallic lithium is used.

Studies in the area of 2,3′-biquinolyl. 1. Arylation and hetarylation of 2,3′-biquinolyl dianion

The 2,3′-biquinolyl dianion, when reacting with aryl- and hetaryl halides, forms arylation products at the 4′ position, and treatment of these products with alkyl halides or water yields 1′-alkyl-4′-aryl-1′,4′-dihydro-2,3′-biquinolyls or 4′-aryl-1′,4′-dihydro-2,3′-biquinolyls, respectively. Oxidation of the latter yields 4′-aryl-2,3′-biquinolyls. The cation dependence of the arylation reaction is demonstrated. 1998 Plenum Publishing Corporation.