206009-40-7Relevant academic research and scientific papers
Investigations of 2,3′-biquinolyl. 9. Reaction of 1′,4′-dihydro-2,3′-biquinolyl with organolithium compounds
Aksenov,Sarapy,Smushkevich
, p. 952 - 955 (2000)
The 1′,4′-dihydro-2,3′-biquinolyl reacts with organolithium compounds to form the mixture of 4′-R-1′,4′-dihydro-2,3′-biquinolyls and 2′-R-1′,2′-dihydro-2,3′-biquinolyls in the ratio analogous to the conversion in the series of 2,3′-biquinolyl. The utiliza
Investigations in the region of 2,3′-biquinoline. 2. Investigation of the nucleophilic addition of organomagnesium compounds and sodium hydride to 2,3′-biquinoline
Aksenov,Nadein,Borovlev,Smushkevich
, p. 207 - 210 (1998)
With sodium hydride and alkyl- and arylmagnesium halides, 2,3-biquinoline forms the products from addition at position 4′, and with allylmagnesium chloride it forms the products from addition at position 2′. Methods were developed for the synthesis of 4′-R-1′,4′-dihydro- and 2′-allyl-1′,2′-dihydro-2,3′-biquinolines. 1998 Plenum Publishing Corporation.
Investigations in the region of 2,3′-biquinoline. 3. Synthesis of 2′-alkyl(aryl)-1′,2′-dihydro-2,3′-biquinolines and 2′-alkyl(aryl)-2,3′-biquinolines
Aksenov,Nadein,Borovlev,Smushkevich
, p. 316 - 320 (1998)
A method was developed for the synthesis of 2′-alkyl(aryl)-1′,2′-dihydro-2,3′-biquinolines, based on the addition of organolithium compounds to 2,3′-biquinoline in the presence of tetramethylethylenediamine. Their oxidation with manganese dioxide led to 2
Studies in the area of 2,3′-biquinolyl. 1. Arylation and hetarylation of 2,3′-biquinolyl dianion
Aksenov,Aksenova,Borovlev,Smushkevich
, p. 954 - 958 (1997)
The 2,3′-biquinolyl dianion, when reacting with aryl- and hetaryl halides, forms arylation products at the 4′ position, and treatment of these products with alkyl halides or water yields 1′-alkyl-4′-aryl-1′,4′-dihydro-2,3′-biquinolyls or 4′-aryl-1′,4′-dihydro-2,3′-biquinolyls, respectively. Oxidation of the latter yields 4′-aryl-2,3′-biquinolyls. The cation dependence of the arylation reaction is demonstrated. 1998 Plenum Publishing Corporation.
Investigation of 2,3′-biquinolyl. 10. The regioselectivity of the reaction of 2,3′-biquinolyl and 1′-alkyl-3-(2-quinolyl)quinolinium halides with halo derivatives in the presence of metallic lithium and magnesium
Aksenov,Nadein
, p. 1314 - 1318 (2007/10/03)
2,3′-Biquinolyl reacts with halo derivatives in the presence of metallic lithium to give addition products at position 4′, treatment of which with water gives 4′-R-1′,4′-dihydro-2,3′-biquinolyls and with halo derivatives gives 1′-alkyl-4′-R-1′,4′-dihydro-2,3′-biquinolyls. The reaction of 2,3′-biquinolyl with halo derivatives in the presence of metallic magnesium gives a mixture of products of addition at positions 2′ and 4′. 1-Alkyl-3-(2-quinolyl)quinolinium halides and halo derivatives with metallic magnesium give 1′-alkyl-2′-R-1′,2′-dihydro-2,3′-biquinolyls but form a complex mixture of substances when metallic lithium is used.
