206055-53-0Relevant articles and documents
LNA (locked nucleic acids): Synthesis and high-affinity nucleic acid recognition
Singh, Sanjay K.,Nielsen, Poul,Koshkin, Alexei A.,Wengel, Jesper
, p. 455 - 456 (2007/10/03)
A novel class of nucleic acid analogues, termed LNA (locked nucleic acids), is introduced. Following the Watson-Crick base pairing rules, LNA forms duplexes with complementary DNA and RNA with remarkably increased thermal stabilities and generally improve