2061-74-7Relevant academic research and scientific papers
Expedited Baeyer-Villiger oxidation of steroidal ketones by microwave irradiation
Borah, Juri Moni,Chowdhury, Pritish
experimental part, p. 1341 - 1345 (2011/11/06)
Microwave (MW) assisted reactions are currently having considerable importance in the synthesis of organic compounds. Considering the remarkable application of Baeyer-Villiger (BV) reaction in the synthesis of natural products and steroid-peptide conjugates, we report here some of our findings of BV oxidation of carbonyl compounds with special reference to steroidal ketones under MW irradiation justifying its accelerating effect.
Ceric ammonium nitrate (CAN) catalyzed Baeyer-Villiger oxidation of carbonyl compounds, specially 20-oxosteroids
Goswami, Papori,Hazarika, Saroj,Das, Archana M.,Chowdhury, Pritish
, p. 1275 - 1281 (2007/10/03)
The role of ceric ammonium nitrate (CAN) as an effective catalyst in the peracid induced Baeyer-Villiger oxidation of carbonyl compounds with special reference to steroids has been demonstrated.
Stereochemical studies. XI. Equilibria between δ-hydroxy-acids and δ-lactones in aqueous tetrahydrofuran. Relative stabilities of isomeric δ-lactones
Edward, John T.,Cooke, Ellen,Paradellis, Themistocles C.
, p. 2546 - 2553 (2007/10/02)
The equilibrium constants K' for the hydrolysis of 13 δ-lactones to hydroxy-acids in 54percent (mol/mol) aqueous tetrahydrofuran at 25 deg C have been determined.The equilibrium constants for the isomerization of the five δ-lactones into their epimers, and for the isomerization of their hydroxy-acids into their epimers, have been calculated by the methods of conformational analysis.These calculated values are consistent with the experimental values of K'.Addition of methyl groups to a hydroxy-acid decreases K' (the Thorpe-Ingold effect).
