20618-92-2

Usage

Uses

Used in Pharmaceutical Industry:
rac 2-Palmitoyl-3-chloropropanediol is used as a pharmaceutical compound for its mutagenic activity. This property allows it to be potentially utilized in the development of new drugs or therapies that target genetic mutations or alterations.
Used in Chemical Research:
In the field of chemical research, rac 2-Palmitoyl-3-chloropropanediol serves as a valuable compound for studying the effects of mutagenic substances on biological systems. Its mutagenic activity can provide insights into the mechanisms of genetic mutations and their implications in various diseases or conditions.
Used in Industrial Applications:
Due to its chemical properties as a fatty acid ester, rac 2-Palmitoyl-3-chloropropanediol may also find use in industrial applications, such as the production of specialty chemicals, additives, or other products that require its specific characteristics.

Upstream product

• 96-24-2 3-monochloro-1,2-propanediol 
• 112-67-4 n-hexadecanoyl chloride 
• 556-52-5 oxiranyl-methanol 
• 69161-79-1 3-Chlor-2-O-palmitoyl-1-O-trityl-propan-1,2-diol 

Relevant academic research and scientific papers

Bidirectional conversion between 3-monochloro-1,2-propanediol and glycidol in course of the procedure of DGF standard methods

NMR observation revealed that bidirectional conversion occurred between 3-monochloropropane-1,2-diol (3-MCPD) and glycidol in the course of the analytical procedure of DFG standard method C-III 18 (09), option A; 3-MCPD was partly converted to glycidol at the transesterification step, and glycidol was converted partly to 3-MCPD at the derivatization step conducted at 80 °C under acidic condition in the presence of NaCl. Based on the proton numbers observed by 1H NMR, the degrees of the conversion were estimated to be 37 and >70%, respectively. In addition, epoxide ring-opening of glycidol and its esters was found to be ca. 90% by the acid treatment described in the method, option B. Thus, it was concluded that the standard method, option A, did not correctly give the combined amount of 3-MCPD esters and glycidyl esters in oils containing glycidyl esters, and the difference of the values obtained by options A and B did not correspond to the amount of glycidyl esters, either. In addition, derivatives of 3-MCPD with phenylboronic acid were not observed by NMR at the derivatization step, although they were detected by GC-MS in the organic phase at the following extraction step.