206182-66-3Relevant articles and documents
Synthesis of 4-benzidinyl butyric acid: A key intermediate for antibodies production against benzidin
Fischer-Durand, Nathalie,Rejeb, Samy Ben,Le Goffic, Francois
, p. 963 - 970 (1998)
A four-step synthesis of monoalkylated benzidin is reported for immunogen preparation against benzidin dye. Use of 10% H2SO4/dioxan for N- Boc cleavage avoids the cyclisation of 4-benzidinyl butyric acid into the corresponding lactam
A fullerene - perylene functional molecule and its preparation method
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Paragraph 0030; 0034; 0035, (2017/06/02)
The invention discloses a fullerene-perylene functional molecule and a preparation method thereof, and relates to the technical field of design and synthesis of functional organic molecules. In a structural general formula, two fullerene pyrrole ring comp
COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF THE ANDROGEN RECEPTOR
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Paragraph 0704; 0705, (2016/08/17)
The present invention relates to bifunctional compounds, which find utility to degrade and (inhibit) Androgen Receptor. In particular, the present invention is directed to compounds, which contain on one end a VHL ligand which binds to the ubiquitin ligase and on the other end a moiety which binds Androgen Receptor such that Androgen Receptor is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of Androgen Receptor. The present invention exhibits a broad range of pharmacological activities associated with compounds according to the present invention, consistent with the degradation/inhibition of Androgen Receptor.