206182-97-0Relevant academic research and scientific papers
Heterocyclic systems containing bridgehead nitrogen atom: Synthesis and bioactivity of 2,3-dihydro-4H-thiazino-as-triazinoindole and quinoxalinothiazoloindolo-as-triazine and their isomeric systems
Mohan, Jag,Kumar, Vineet
, p. 95 - 97 (2007/10/03)
2,3-Dihydro-7-methyl-5H-as-triazinoindole-3-thione 2 on condensation with 1,3-dibromopropane and 2,3-dichloroquinoxaline gives the cyclized products, 2,3-dihydro-9-methyl-4H-thiazino-as-triazinoindole 4 and 10-methylquinoxalinothiazoloindolo-as-triazine 6 respectively and not the angular isomers, 2,3-dihydro-9-methyl-1H-thiazino-as-triazinoindole 3 and 2-methylquinoxalinothiazoloindolo-as-triazine 5.The uniquivocal synthesis of the latter 3 and 5 have been accomplished by reaction of 6-methylisatin-3-thiosemicarbazone 1 with 1,3-dibromopropane and 2,3-dichloroquinoxalines, respectively.The antibacterial and antifungal activity of the synthesized compounds have also been evaluated.
Condensed bridgehead nitrogen heterocyclic systems: Synthesis and antimicrobial activity of thiazolo[3′,2′:2,3]-as-triazino[5,6-b]indoles and isomeric thiazolo[2′,3′:3,4]-as-triazino[5,6-b]indoles
Mohan, Jag,Kumar, Vineet
, p. 1030 - 1033 (2007/10/03)
2,3-Dihydro-7-methyl-5H-as-triazino[5,6-6]indole-3-thione 4 on condensation with α-haloketones gives 3-aroylmethylthio-7-methyl-5H-as-triazino[5,6-6]indole hydrobromides 5 which on PPA catalysed cyclisation furnishes 3-aryl-8-methylthiazolo[3′,2′:2,3]-as-
