206195-70-2

Upstream product

• 16697-49-7 3,4,6-tri-O-benzyl-1,2-O-(methoxyethylidene)-β-D-mannopyranose 
• 645-96-5 Benzeneselenol 
• 152697-19-3 phenyl 2-O-acetyl-3,4,6-tri-O-Benzyl-1-seleno-α-D-mannopyranoside 

Downstream Products

• 254444-15-0 Phenyl 3,4,6-tri-O-benzyl-1-seleno-2-O-allyloxycarbonyl-α-D-mannopyranoside 
• 254444-10-5 Phenyl 3,4,6-tri-O-benzyl-1-seleno-2-O-(2',2',2'-trichloroethoxycarbonyl)-α-D-mannopyranoside 
• 254444-67-2 Methyl 2,4-di-O-benzyl-3-O-[3,4,6-tri-O-benzyl-2-O-(2',2',2'-trichloroethoxycarbonyl)-α-D-mannopyranosyl]-6-O-tert-butyldiphenylsilyl-α-D-mannopyranoside 
• 254444-13-8 Methyl 2,4-di-O-benzyl-3-O-[3,4,6-tri-O-benzyl-2-O-(2',2',2'-trichloroethoxycarbonyl)-α-D-mannopyranosyl]-α-D-mannopyranoside 

Relevant academic research and scientific papers

Synthesis of glycans from the glycodelins: Two undeca-, two deca-, three nona-, an octa- and a heptasaccharide

The concise synthesis of nine diantennary oligosaccharides by chemical and chemoenzymatic protocols is presented. The compounds display Lewis X, Lewis Y, sialyl Lewis X and T-antigen epitopes supported on a 3,6-branched trimannose core. A chemical approach was adopted for the synthesis of the unsymmetrically decorated structures and those that could not be accessed by enzymatic decoration of a core heptasaccharide.

Synthesis of C-glycosyl lactones and protected C-glycosyl amino acids: Use of radical cyclization

Protected carbohydrates 6a-13a, having one free hydroxyl and a phenylseleno group or halogen on the adjacent carbon, were condensed with (2,2-diphenylhydrazono)acetic acid (2); the resulting esters undergo radical cyclization to afford carbohydrates fused to a 2,2-diphenylhydrazino lactone unit (6c,d-13c,d). In suitable cases (9c,d) such carbohydrate lactones can be elaborated into C-glycosyl amino acids.