152697-19-3Relevant articles and documents
1,2,5-Ortho esters of D-arabinose as versatile arabinofuranosidic building blocks. Concise synthesis of the tetrasaccharidic cap of the lipoarabinomannan of Mycobacterium tuberculosis
Bamhaoud, Toufiq,Sanchez, Sylvie,Prandi, Jacques
, p. 659 - 660 (2007/10/03)
1,2,5-ortho esters of D-arabinose were found to be ideally suited building blocks for the stereoselective formation of and β arabinofuranosidic linkages after nucleophilic opening of the orthoester with oxygen and sulfur nucleophiles; the tetrasaccharidic cap of the lipoarabinomannan of Mycobacterium tuberculosis was then synthesized in a highly convergent manner.
Synthesis of high-mannose type neoglycolipids: Active targeting of liposomes to macrophages in gene therapy
Dueffels, Arno,Green, Luke G.,Ley, Steven V.,Miller, Andrew D.
, p. 1416 - 1430 (2007/10/03)
The concise synthesis of five biantennary oligomannose neoglycolipids is presented. Employing a strategy based on the principles of reactivity tuning and orthogonal activation, the oligomannose moieties, isolated from the glycoprotein 63 of the parasite L
Synthesis of glycans from the glycodelins: Two undeca-, two deca-, three nona-, an octa- and a heptasaccharide
Depre, Dominique,Dueffels, Arno,Green, Luke G.,Lenz, Roman,Ley, Steven V.,Wong, Chi-Huey
, p. 3326 - 3340 (2007/10/03)
The concise synthesis of nine diantennary oligosaccharides by chemical and chemoenzymatic protocols is presented. The compounds display Lewis X, Lewis Y, sialyl Lewis X and T-antigen epitopes supported on a 3,6-branched trimannose core. A chemical approach was adopted for the synthesis of the unsymmetrically decorated structures and those that could not be accessed by enzymatic decoration of a core heptasaccharide.
Chemical synthesis of the W-glycans of gp63, the major surface glycoprotein from Leishmania mexicana amazonemis
Duffels, Arno,Ley, Steven V.
, p. 375 - 378 (2007/10/03)
The chemical synthesis of the conjugated heptasaccharide Man(α1-3)Man(α1-6)[GIc(α1-3)Man(α1-2)Man(α1-2) Man(α1-3)]Manβl-O[CH2]8CO2Me 1 and four closely related biantennary oligomannose type structures derived from the glyc