206271-42-3Relevant academic research and scientific papers
New MCR based on intramolecular Heck reaction under aerobic conditions: A direct access to cytotoxic fused N-heterocycles
Adepu, Raju,Prasad, Bagineni,Ashfaq, Mohd Ashraf,Ehtesham, Nasreen Z.,Pal, Manojit
, p. 49324 - 49328 (2014)
We report a new MCR involving the reaction of isatoic anhydrides, allyl amine and o-bromo arylaldehydes in the presence of Pd(OAc)2, X-Phos and air to afford various isoquinolino[1,2-b]quinazolinones as new cytotoxic agents. The strategy was extended successfully towards the synthesis of a methyl analogue of 7,8-dehydrorutaecarpine. This journal is
Palladium functionalized phosphinite polyethyleneimine grafted magnetic silica nanoparticles as an efficient catalyst for the synthesis of isoquinolino[1,2-: B] quinazolin-8-ones
Bahadorikhalili, Saeed,Mahdavi, Mohammad,Ma'Mani, Leila,Shafiee, Abbas,Mahdavi, Hossein,Akbarzadeh, Tahmineh
, p. 5499 - 5507 (2018)
In this paper, a novel methodology is introduced for the synthesis of novel 5-methyl-8H-isoquinolino[1,2-b]quinazolin-8-one derivatives based on an efficient immobilized palladium catalyzed intramolecular carbon-carbon bond formation. The novel catalyst i
Tetracyclic isoquinolones and quinazolones via aryl radical cyclizations
Banik, Bimal K.,Raju, Vegesna S.,Manhas, Maghar S.,Bose, Ajay K.
, p. 639 - 642 (2007/10/03)
The Schiff base from o-bromobenzaldehyde and allylamine was allowed to react with homophthalic anhydride to form an isoquinolone. Reaction of the same Schiff base with isatoic anhydride led to a quinazolone. Generation of a free radical from the bromoaryl
