206271-42-3

Basic information

• Product Name: 3-allyl-2-(2-bromophenyl)-2,3-dihydroquinazolin-4(1H)-one
• Synonyms: 3-allyl-2-(2-bromophenyl)-2,3-dihydroquinazolin-4(1H)-one
• CAS NO: 206271-42-3
• Molecular Weight: 343.223
• Mol File: 206271-42-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-allyl-2-(2-bromophenyl)-2,3-dihydroquinazolin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-allyl-2-(2-bromophenyl)-2,3-dihydroquinazolin-4(1H)-one(206271-42-3)
• EPA Substance Registry System: 3-allyl-2-(2-bromophenyl)-2,3-dihydroquinazolin-4(1H)-one(206271-42-3)

Safety Data

• Hazardous Substances Data: 206271-42-3(Hazardous Substances Data)

Upstream product

• 4943-82-2 N-allyl-2-aminobenzamide 
• 6630-33-7 ortho-bromobenzaldehyde 
• 118-48-9 isatoic anhydride 
• 107-11-9 1-amino-2-propene 
• 175853-25-5 Allyl-[1-(2-bromo-phenyl)-meth-(Z)-ylidene]-amine 

Relevant articles and documents

New MCR based on intramolecular Heck reaction under aerobic conditions: A direct access to cytotoxic fused N-heterocycles

We report a new MCR involving the reaction of isatoic anhydrides, allyl amine and o-bromo arylaldehydes in the presence of Pd(OAc)2, X-Phos and air to afford various isoquinolino[1,2-b]quinazolinones as new cytotoxic agents. The strategy was extended successfully towards the synthesis of a methyl analogue of 7,8-dehydrorutaecarpine. This journal is

Tetracyclic isoquinolones and quinazolones via aryl radical cyclizations

The Schiff base from o-bromobenzaldehyde and allylamine was allowed to react with homophthalic anhydride to form an isoquinolone. Reaction of the same Schiff base with isatoic anhydride led to a quinazolone. Generation of a free radical from the bromoaryl