20635-30-7

Usage

Uses

Used in Pharmaceutical Industry:
Terephthalaldehyde bis(diethyl acetal) is used as a key intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs and medicines.
Used in Agrochemical Industry:
TEREPHTHALALDEHYDE BIS(DIETHYL ACETAL) is utilized as an intermediate in the production of agrochemicals, aiding in the creation of effective pesticides and other agricultural products.
Used in Fine Chemicals Industry:
Terephthalaldehyde bis(diethyl acetal) is employed in the synthesis of fine chemicals, which are essential for various applications, including specialty chemicals and high-value products.
Used in Polymer Production:
It is used as a component in the production of high-performance polymers, which are crucial for manufacturing durable and high-quality materials.
Used in Organic Synthesis:
As a reagent in organic synthesis, terephthalaldehyde bis(diethyl acetal) plays a significant role in facilitating various chemical reactions, leading to the formation of desired products.
Used in Perfumery:
TEREPHTHALALDEHYDE BIS(DIETHYL ACETAL) is used as a fragrance ingredient in perfumes, adding to the complexity and richness of scents in various fragrances.
Used in Food Industry:
Terephthalaldehyde bis(diethyl acetal) is utilized as a flavoring agent in the food industry, enhancing the taste and aroma of food products.

Upstream product

• 623-27-8 terephthalaldehyde, 
• 122-51-0 orthoformic acid triethyl ester 
• 1592-31-0 1,4-bis(dibromomethyl)benzene 

Downstream Products

• 101403-67-2 C₄₈H₅₀O₈ 
• 137585-08-1 tetraethyl 2,2'-(benzene-1,4-diyl)bis[(4R,5R)-1,3-dioxolane-4,5-dicarboxylate] 
• 77972-48-6 styrene-α,4-dicarbaldehyde 
• 3049-37-4 1,4-bis(2-formylethenyl)benzene 

Relevant academic research and scientific papers

Synthesis of 4-(Dibromomethyl)benzaldehyde by Catalytic Debromophosphoryl- and Phosphonyloxylation of 1,4-Bis(dibromomethyl)benzene with Phosphorus(IV) Acid Methyl Esters and Its Properties

A new procedure has been developed for the simultaneous preparation of terephthalaldehyde and 4-(dibromomethyl)benzaldehyde by catalytic debromophosphoryl- and phosphonyloxylation of 1,4-bis- (dibromomethyl)benzene with P(IV) acid methyl esters. The reaction of 4-(dibromomethyl)benzaldehyde with ortho esters in the presence of sulfuric acid gave the corresponding acetals, whereas in the presence of ZnCl2 terephthalaldehyde bis-acetals were formed. 4-(Dibromomethyl)benzaldehyde and its acetal were converted to methyl 4-(dibromomethyl)- and 4-(dimethoxymethyl)benzoates which were phosphorylated by the action of chlorophosphines, as well as by successive treatment with phosphorus(III) chloride and P(III) esters.

Effect of the Catalyst Nature on the Structure of Products of the Reaction of 4-(Dibromomethyl)Benzaldehyde with Trialkyl Orthoformates

Reactions of 4-(dibromomethyl)benzaldehyde with trialkyl orthoformates in the presence of both Br?nsted (H2SO4) and Lewis (ZnCl2) acids involved acetalization of the aldehyde group. In the first case, the corresponding acetal is formed as the only product, whereas in the second case the reaction is accompanied by transformation of the dibromomethyl group to give terephthalaldehyde and its mono- and bis-acetals.

Synthesis of aromatic aldehyde acetals from (dibromomethyl)arenes

Zinc chloride-catalyzed double debromoalkoxylation of (dibromomethyl)arenes on treatment with trialkyl orthoformates resulted in the corresponding aromatic aldehyde acetals. On the first step, α-brominated ether is formed, which undergoes the second debro