206355-16-0Relevant academic research and scientific papers
Effect of various pyrimidines possessing the 1-[(2-hydroxy-1- (hydroxymethyl)ethoxy)methyl] moiety, able to mimic natural 2′- deoxyribose, on wild-type and mutant hepatitis B virus replication
Kumar, Rakesh,Semaine, Wassila,Johar, Monika,Tyrrell, D. Lorne J.,Agrawal, Babita
, p. 3693 - 3700 (2006)
Hepatitis B virus (HBV) is the most common cause of chronic liver disease worldwide. Development of drug resistance against clinical anti-HBV drug lamivudine due to long-term use and rebound of viral DNA after cessation of treatment has been a major setba
