206554-92-9Relevant academic research and scientific papers
Solution phase combinatorial chemistry. Discovery of 13- and 15-membered polyazapyridinocyclophane libraries with antibacterial activity
An, Haoyun,Wang, Tingmin,Mohan, Venkatraman,Griffey, Richard H.,Dan Cook
, p. 3999 - 4012 (1998)
A solution phase simultaneous addition of functionalities (SPSAF) combinatorial approach was utilized to synthesize 40 polyazacyclophane libraries (total complexity of 4275). Eighteen different functionality sets, utilizing 42 functionalities, were design
TRICYCLIC DEGRADERS OF IKAROS AND AIOLOS
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Page/Page column 497-498, (2020/10/21)
Tricyclic cereblon binders for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway for therapeutic applications are described.
Benzoate compound as well as preparation method and application thereof
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Paragraph 0039; 0040; 0041, (2018/06/28)
The invention relates to a benzoate compound as well as a preparation method and application thereof. The small-molecule compound is the benzoate compound, namely, (E)-methyl4-((4-(4-(4-(3-methoxy-3-oxoprop-1-en-1-yl)benzoyl)piperazinenzoyl)piperazinenzoy
Sulfonamide derivatives, their production and use
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Referential example 1, (2010/11/29)
The present invention provides compounds which specifically inhibit FXa, which are effective when orally administered and which are useful as a safe medicine for the prevention or treatment of diseases caused by thrombus or infarction. Compounds of this invention are piperazinones of the formula: wherein R1is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group; the ring A is an optionally substituted divalent nitrogen-containing heterocyclic group, in addition to being substituted by the group of the formula: and the group of the formula: Y is an optionally substituted divalent hydrocarbon group or an optionally substituted divalent heterocyclic group; X is a direct bond or an optionally substituted alkylene chain; Z is (1) an amino group substituted with an optionally substituted hydrocarbon group, (2) an optionally substituted imino group or (3) an optionally substituted nitrogen-containing heterocyclic group; provided that when X is a direct bond and Z is an optionally substituted 6-membered nitrogen-containing aromatic heterocyclic group, Y is an optionally substituted divalent hydrocarbon group or an optionally substituted divalent unsaturated heterocyclic group; or a salt thereof.
Substituted cyclic compounds and mixtures comprising same
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, (2008/06/13)
Novel chemical compounds and mixtures of same are provided having antibacterial and other utilities. The mixtures preferably are formed by reacting a cyclic scaffold moiety with a set of chemical substituients. Libraries formed in accordance with the inve
