Solution phase combinatorial chemistry. Discovery of 13- and 15-membered polyazapyridinocyclophane libraries with antibacterial activity

DOI: 10.1016/S0040-4020(98)00131-8

Source and publish data:

Tetrahedron p. 3999 - 4012 (1998)

Update date:2022-08-03

Topics:

Authors:

An, Haoyun

Wang, Tingmin

Mohan, Venkatraman

Griffey, Richard H.

Dan Cook

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(98)00131-8

A solution phase simultaneous addition of functionalities (SPSAF) combinatorial approach was utilized to synthesize 40 polyazacyclophane libraries (total complexity of 4275). Eighteen different functionality sets, utilizing 42 functionalities, were design

Full text of DOI:10.1016/S0040-4020(98)00131-8

Products guided by the article

Product name:tert-butylpiperazine-4-[[(4′-chloromethyl)benzoyl]-1′-carbonyl]-1-carboxylate

Cas No:206554-92-9

R&D Labs maybe for 206554-92-9

ENERGYCO LTD.

Contact:+86-25-83719363

Address:106-7 Chunnan Rd, Chunxi Town, Gaochun, Nanjing, China
Henan Harvest Chem Co., Ltd

Contact:+86-371-86058576

Address:NO.32, Jingsan Road, Zhengzhou, China
Nanjing distinctions Medical Technology Co., Ltd.(expird)

Contact:+86-15996203785 13914714059

Address:nanjing,jiangsu , China
Weifang Dongxing Chitosan Factory

website:http://dxchitosan.lookchem.com/

Contact:13475651157

Address:Weifang city ,shandong province
Huludao Tianqi Shengye Chemical Co.,Ltd.

Contact:0086 429 2075777

Address:Area B,Shipbuilding Industry Park,Beigang District,Huludao City,Liaoning prov.,China

Relevant to this article

A highly selective fluorescent probe for thiophenols

Doi:10.1002/anie.200702271
(2007)
Carrier-free cellular uptake and the gene-silencing activity of the lipophilic siRNAs is strongly affected by the length of the linker between siRNA and lipophilic group

Doi:10.1093/nar/gkr1002
(2012)
Doi:10.1016/0045-6535(73)90052-0
(1973)
The palladium-catalyzed carbonylation of nitrobenzene into phenyl isocyanate: The structural characterization of a metallacylic intermediate

Doi:10.1021/om9708485
(1998)
Continued optimization of the M₅NAM ML375: Discovery of VU6008667, an M₅NAM with high CNS penetration and a desired short half-life in rat for addiction studies

Doi:10.1016/j.bmcl.2017.02.020
(2017)
Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression

Doi:10.1021/acs.jmedchem.6b01816
(2018)

Article Doi