206555-31-9Relevant academic research and scientific papers
Synthesis of 4,6-bis(1H-1,2,3-triazolyl)pyrimidines by the reaction of 4,6-diazido-2-(4-methoxyphenyl)pyrimidine with compounds containing a reactive methylene group
Nikolaenkova,Krivopalov
, p. 968 - 972 (1997)
The reaction of 4,6-diazido-2-(4-methoxyphenyl)pyrimidine with cyanoacetic ester in the presence of triethylamine leads only to 4-azido-6-amino-1-(4-methoxyphenyl)pyrimidine. The main product in reactions with 1,3-dicarbonyl compounds (acetylacetone, acetoacetic and benzoylacetic esters) is the corresponding substituted 4,6-bis(1H-1,2,3-triazolyl)pyrimidine. Theformation of4-azido-6-(1H-1,2,3-triazolyl)pyrimidine and4-amino-6-(1H-1,2,3-triazolyl)pyrimidine as minor products was also recorded. 1998 Plenum Publishing Corporation.
