83217-08-7

Upstream product

• 51721-68-7 4-methoxybenzamidine hydrochloride 
• 874-90-8 4-methoxybenzonitrile 
• 123-11-5 4-methoxy-benzaldehyde 
• 15726-40-6 2-(4-methoxyphenyl)-4,6-dihydroxypyrimidine 
• 26863-52-5 2-(4-methoxy-phenyl)-1H-pyrimidine-4,6-dione 

Downstream Products

• 64398-21-6 4-aziridin-1-yl-6-chloro-2-(4-methoxy-phenyl)-pyrimidine 
• 206555-31-9 4,6-diazido-2-(4'-methoxyphenyl)pyrimidine 
• 565470-12-4 C₈₇H₁₀₂N₆O₇ 
• 565470-09-9 4-[4,6-bis-(3,5-di-tert-butyl-phenoxy)-pyrimidin-2-yl]-phenol 
• 565470-07-7 4,6-bis-(3,5-di-tert-butyl-phenoxy)-2-(4-methoxy-phenyl)-pyrimidine 

Relevant academic research and scientific papers

Structure-activity relationships of 2, 4-disubstituted pyrimidines as dual ERα/VEGFR-2 ligands with anti-breast cancer activity

Both ERα and VEGFR-2 are important targets for cancer therapies. Here a series of 2, 4-disubstituted pyrimidine derivatives were designed, synthesized and evaluated as dual ERα/VEGFR-2 ligands. Most of the derivatives exhibited potent activities in both e

meso-Pyrimidinyl-substituted A2B-corroles

meso-Pyrimidinyl-substituted A2B-corroles were synthesized in good yields by condensation of 5-mesityldipyrromethane and 2-substituted 4,6-dichloropyrimidine-5-carbaldehydes. A simple reduction of the amount of Lewis acid (BF3-OEtsu

Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants

This invention is directed to aryl and heterocyclyl substituted pyrimidine derivatives selected from the following formulae: wherein Z1, Z2, R1, R2, R3, R4, R5and R6are defined herein. These compounds are useful as anti-coagulants.

Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants

This invention is directed to aryl and heterocyclyl substituted pyrimidine derivatives selected from the following formulae: wherein Z1, Z2, R1, R2, R3, R4, R5 and R6 are defined herein. These compounds are useful as anti-coagulants.