206555-77-3 Usage
Description
4-(2-AMINO-THIAZOL-4-YL)-BENZOIC ACID METHYL ESTER is a chemical compound characterized by the molecular formula C11H10N2O2S. It is a methyl ester derivative of benzoic acid, featuring a thiazole ring and an amino group. 4-(2-AMINO-THIAZOL-4-YL)-BENZOIC ACID METHYL ESTER is recognized for its role as a building block in the synthesis of various bioactive molecules and pharmaceuticals, making it a valuable intermediate in the production of diverse chemical compounds with potential applications in the pharmaceutical and agrochemical industries.
Uses
Used in Organic Synthesis:
4-(2-AMINO-THIAZOL-4-YL)-BENZOIC ACID METHYL ESTER is used as a key intermediate in organic synthesis for the creation of a variety of chemical compounds. Its unique molecular structure, which includes a thiazole ring and an amino group, allows for the development of new molecules with specific properties and functions.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 4-(2-AMINO-THIAZOL-4-YL)-BENZOIC ACID METHYL ESTER is utilized as a building block for the synthesis of bioactive molecules. Its presence in the molecular structure of target compounds can contribute to their pharmacological activity, making it an essential component in drug discovery and development processes.
Used in Agrochemical Industry:
4-(2-AMINO-THIAZOL-4-YL)-BENZOIC ACID METHYL ESTER is also employed in the agrochemical industry, where it serves as a precursor for the synthesis of agrochemicals with potential applications in pest control and crop protection. Its versatility in chemical reactions enables the production of a range of agrochemicals with different modes of action and target pests.
Check Digit Verification of cas no
The CAS Registry Mumber 206555-77-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,6,5,5 and 5 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 206555-77:
(8*2)+(7*0)+(6*6)+(5*5)+(4*5)+(3*5)+(2*7)+(1*7)=133
133 % 10 = 3
So 206555-77-3 is a valid CAS Registry Number.
206555-77-3Relevant articles and documents
2-Amino-4-arylthiazoles through One-Pot Transformation of Alkylarenes with NBS and Thioureas
Shibasaki, Kaho,Togo, Hideo
, p. 2520 - 2527 (2019/04/04)
Treatment of alkylarenes with N-bromosuccinimide in a mixture of ethyl acetate and water at 60 °C, a mixture of acetonitrile and water at 80 °C, or a mixture of diethyl carbonate and water under irradiation with a tungsten lamp, followed by a reaction with thioureas or arenethioamides provided the corresponding 2-amino- 4-arylthiazoles or 2,4-diarylthiazoles in good to moderate yields, respectively, in one pot. The present reaction is an efficient one-pot transformation method of alkylarenes into 2-amino-4-arylthiazoles and 2,4-diarylthiazoles directly under mild and transition-metal-free conditions.
4 - substituted -2 - amino thiazole compound preparation method
-
Paragraph 0024; 0025; 0026; 0027; 0028; 0029-0044; 0075-0079, (2017/08/24)
The invention discloses a preparation method of a 4-substituted-2-aminothiazole compound. The method comprises the following step: olefin azide shown by the formula I reacts with potassium thiocyanate under the catalysis of palladium acetate to obtain the 4-substituted-2-aminothiazole compound, wherein the molar ratio of the olefin azide compound to potassium thiocyanate to palladium acetate is 20:(59-61):1, the reaction temperature is 75-85 DEG C, and the reaction time is 11-13 hours; and in the formula I, R1 is phenyl, 2-bromophenyl, 3-bromophenyl, 4-bromophenyl, 4-methylphenyl, 4-ethyoxy-3-bromophenyl, 3-nitrophenyl, 4-methoxyacylphenyl, 1-naphthyl, phenylaminomethyl or trans-4-(3-phenylallyloxymethyl).
Design and synthesis of 2-aminothiazole based antimicrobials targeting MRSA
Annadurai, Sivakumar,Martinez, Rogelio,Canney, Daniel J.,Eidem, Tess,Dunman, Paul M.,Abou-Gharbia, Magid
supporting information, p. 7719 - 7725 (2013/02/21)
Privileged structure-based libraries have been shown to provide high affinity lead compounds for a variety of important biological targets. The present study describes the synthesis and screening of a 2-aminothiazole based compound library to determine th
