206559-48-0

Usage

Uses

Used in Pharmaceutical Research:
4-(4-Carboxyphenyl)-3-thiosemicarbazide is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure and functional groups make it a valuable building block in the development of new drugs for the treatment of different diseases.
Used in Drug Development:
4-(4-Carboxyphenyl)-3-thiosemicarbazide is used as a potential drug candidate in the discovery and development of new therapeutic agents. Its ability to form various chemical bonds and interact with biological targets makes it a promising candidate for the treatment of various medical conditions.
Used in Chemical Synthesis:
4-(4-Carboxyphenyl)-3-thiosemicarbazide is used as a reagent in various chemical reactions, enabling the synthesis of a wide range of organic compounds. Its versatility and reactivity make it a valuable component in the preparation of complex molecules and materials.
Used in Research and Development:
4-(4-Carboxyphenyl)-3-thiosemicarbazide is used as a research tool in the study of chemical properties, reactions, and mechanisms. Its unique structure and potential applications make it an interesting subject for further investigation and exploration in the field of chemistry.

InChI:InChI=1/C8H9N3O2S/c9-11-8(14)10-6-3-1-5(2-4-6)7(12)13/h1-4H,9H2,(H,12,13)(H2,10,11,14)

Upstream product

• 75-15-0 carbon disulfide 
• 150-13-0 4-amino-benzoic acid 
• 2131-62-6 4-isothiocyanatobenzoic acid 

Downstream Products

• 1180528-33-9 (Z)-4-(2-(2-oxoindolin-3-ylidene)hydrazinecarbothioamido)benzoic acid 

Relevant academic research and scientific papers

Heterocyclization of Aromatic Amino Acids: Novel Syntheses and Antibacterial Activity of Fused, Non-fused, and Spiro Polyheterocyclic Derivatives

Abstract: Commercially available p-aminobenzoic acidwas used as a precursor for the synthesis of novel fused, non-fused, and spiropolyheterocyclic derivatives bearing indene, imidazole, pyrazole, and/ortriazine nucleus via addition to simple and accessibl

Synthesis and anticonvulsant and neurotoxicity evaluation of N 4-phthalimido phenyl (thio) semicarbazides

The phenyl (thio) semicarbazide derivatives of phthalimido pharmacophore were synthesized and evaluated for their anticonvulsant and neurotoxic properties. Initial anticonvulsant screening was performed using intraperitoneal (i.p.), maximal electroshock-induced seizure (MES), subcutaneous pentylenetetrazole (scPTZ) and subcutaneous strychnine (sc STY)-induced seizure threshold tests in mice. Compound 2c afforded protection in all the three screens. Compounds except 1d, 2a and 2d showed no neurotoxicity up to 300mg/kg. Compounds 1a, 1b, 2c, 2d, 2g and 2i were found to show oral MES activity. The compounds exhibited CNS depression and behavioral despair side effects, lesser than the conventional antiepileptic drugs.

Identification of a pharmacophore for thrombopoietic activity of small, non-peptidyl molecules. 1. Discovery and optimization of salicylaldehyde thiosemicarbazone thrombopoietin mimics

High-throughput screening has resulted in the discovery of thiosemicarbazone thrombopoietin mimics. A shared pharmacophore hypothesis between this series and a previously identified class, the pyrazol-4-ylidenehydrazines, led to the rapid optimization of