20659-68-1

Usage

Enantiomer

R-methylbenzyl methyl ketone (3-methyl-1-phenyl-1-pentanone)

Uses

Building block in organic synthesis, precursor in production of pharmaceuticals, fragrances, and flavoring agents

Physical properties

Colorless liquid, sweet and floral odor, flammable and volatile

Toxicity

Low, but should be handled with care to avoid inhalation or skin contact

Upstream product

• 29394-58-9 (S)-1-iodo-2-methyl-butane 
• 53178-41-9 2-lithio-2-phenyl-1,3-dithiane 
• 28977-69-7 (S)-3-methylpentanoic acid chloride 
• 71-43-2 benzene 
• 35660-91-4 (E)-1-phenyl-2-buten-1-one 
• 557-20-0 diethylzinc 
• 534-00-9 (S)-2-methylbutyl bromide 
• 1730-92-3 (3S)-methylvaleric acid 
• 495-41-0 1-phenylbut-2-en-1-one 
• 28977-69-7 α(+)-2-Methylvalerylchlorid 
• 137-32-6 (+/-)-2-methyl-1-butanol 
• 105-43-1 (S)-3-methyl-pentanoic acid 

Downstream Products

• 78976-22-4 (S)-(+)-1-(3-Methylpentyl)-4-nitrobenzol 
• 78976-21-3 (S)-(+)-1-(3-Methylpentyl)-2-nitrobenzol 
• 79027-65-9 cis-(S,S)-(+)-4,4'-Bis(3-methylpentyl)azobenzol 
• 79027-66-0 trans-(S,S)-(+)-4,4'-Bis(3-methylpentyl)azobenzol 
• 78976-10-0 cis-(S,S)-(-)-2,2'-Bis(3-methylpentyl)azobenzol 
• 78976-11-1 trans-(S,S)-(-)-2,2'-Bis(3-methylpentyl)azobenzol 
• 26372-59-8 (S)-(+)-3-Methyl-1-phenylpentan 

Relevant academic research and scientific papers

Oxidative C-C bond cleavage of aldehydes via visible-light photoredox catalysis

The visible-light mediated oxidative C-C bond cleavage of aldehydes has been achieved in good yields at ambient temperature and open to air using Ru(bpy)3Cl2 (bpy = 2,2′-bipyridine) as the photoredox catalyst. Moreover, we further demonstrated the application in a tandem Michael/oxidative C-C bond cleavage reaction.

Enantioselective conjugate addition of dialkylzincs to α,β- unsaturated enones catalyzed by Ni(acac)2 and (+)-(1S,2R)-7,7- dimethyl-1-morpholinoisonorborneol

A mixture of chiral ligand 4 [(+)-MINBOL] and Ni(acac)2 (12.5 and 0.5 mol % respectively) is able to successfully catalyze the enantioselective conjugate 1,4-addition of dialkylzinc to α,β- unsaturated enones in propionitrile to give the corres

Enantioselective 1,4-conjugate addition of diethylzinc to (E)-alkenyl aryl ketones catalysed by Cu/DiPPAM complex

We report here the use of the DiPPAM-L1 ligand for copper-catalysed asymmetric conjugate addition (ACA) of diethylzinc to various (E)-alkenyl aryl ketones where the aryl ring is either a phenyl group substituted by nitro, chloro or methoxy groups or not s

METHOD OF ENANTIOSELECTIVE ADDITION TO ENONES

The present invention relates to a method of enantioselective addition to enones, including: reacting R3(CH2)pCH═CR5C(═O)Y(CH2)qR4 with R6ZnR7 in the presen

Construction of a new type of chiral bidentate NHC ligands: copper-catalyzed asymmetric conjugate alkylation

We synthesized in three steps simple chiral bidentate NHC compounds that carry an achiral coordinating group as N-substituent and revealed that they serve as efficient chiral auxiliaries for the copper-catalyzed asymmetric conjugate addition of dialkylzin

Application of ferrocenyl substituted aziridinylmethanols (FAM) as chiral ligands in enantioselective conjugate addition of diethylzinc to enones

Easily available ferrocenyl substituted aziridinylmethanol FAM-4a complexes with nickel and catalyzes the enantioselective diethylzinc addition to various enones with enantiomeric excesses reaching 80%. The ligand can be recovered and used without losing its activity. The sense of induction was found to be dependent on the configuration of the aziridine ring.

2-Amino-1-phenyl-1,3-propanediol Derivatives. New Ligands for Asymetric 1,4-Addition of Organozinc Reagents to Enones

In the presence of (1S,2S)-3-benzyloxy-2-morpholino-1-phenylpropanol derived readily from (1S,2S)-2-amino-1-phenyl-1,3-propanediol and nickel acetylacetonate, diethylzinc added to α,β-unsaturated ketones to give alkylated product in high optical purity (u

The Effect of Methyl Group Position in Branched Alkyl Chains on the Phenolic End of 4,4'-Disubstituted Phenylbenzoates on Mesomorphic Properties and Some Optically Active Analogs as Ferroelectric Liquid Crystals

A select number of homologs of the branched chain (BC) C5 ester series: in which m=0-3 and n=0-2, and X=R, RO, and C9CO2 have been synthesized to study the effect of branching and the position of the branching methyl group on mesomorphic propert

Synthese chiraler Azobenzole und Untersuchung der in nematischen Fluessigkristallen durch sie induzierten cholesterischen Phasen

The chiral cis- and trans-azo compounds 8a - d and 9a - d with para- or ortho-standing chiral side chains as well as the trans-azoxy derivatives 17a - d and 18a - d are synthesized.The influence of the molecular structure and the distance of the chiral centre from the aromatic nucleus on screw sense and pitch of induced cholesteric phases is investigated.The cis-azo compounds 9c and d show atropisomerism.