206751-16-8Relevant academic research and scientific papers
The alkyne pathway to keramadine from the marine sponge Agelas sp.
Lindel, Thomas,Hochguertel, Matthias
, p. 2541 - 2544 (1998)
A novel synthesis of the pyrrole-imidazole alkaloid keramadine (1) from the marine sponge Agelas sp. is described. Regiocontrol is reached by the Pd- catalyzed alkynylation of 1-benzenesulfonyl-4-iodoimidazole, followed by N- methylation employing trimeth
