Tetrahedron Letters p. 2541 - 2544 (1998)
Update date:2022-09-26
Topics:
Lindel, Thomas
Hochguertel, Matthias
A novel synthesis of the pyrrole-imidazole alkaloid keramadine (1) from the marine sponge Agelas sp. is described. Regiocontrol is reached by the Pd- catalyzed alkynylation of 1-benzenesulfonyl-4-iodoimidazole, followed by N- methylation employing trimeth
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Doi:10.1016/S0040-4020(98)00192-6
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