206767-52-4

Upstream product

• 114547-22-7 1-(3,4-dimethoxy-5-nitrophenyl)-2-nitroethane 
• 114547-23-8 2,3-dimethoxy-5-(2-nitroethyl)aniline 
• 22027-96-9 5-nitroveratral 
• 114547-21-6 (E)-1-(3,4-dimethoxy-5-nitrophenyl)-2-nitroethene 

Downstream Products

• 206767-54-6 4-[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-ethyl]-1-(4-fluoro-phenyl)-6,7-dimethoxy-1H-indole-2,3-dione 
• 206767-53-5 2-{2-[3-(4-Fluoro-phenylamino)-4,5-dimethoxy-phenyl]-ethyl}-isoindole-1,3-dione 
• 206767-55-7 2-[1-(4-Fluoro-phenyl)-6,7-dimethoxy-1H-indol-4-yl]-ethylamine 
• 206767-66-0 [5-(2-Amino-ethyl)-2,3-dimethoxy-phenyl]-(4-fluoro-phenyl)-amine 

Relevant academic research and scientific papers

Azepinoindole derivatives with high affinity for brain dopamine and serotonin receptors

We synthesized 20 and 21 as conformationally constrained analogues of the dopamine receptor antagonist SKF-83742, as well as analogues 6-9, 16, and 18-22. Although 20 and 21 were inactive, 7, 9, and 19 showed strong binding to D-1, D-2, S-2, and α-1 receptors, as well as antipsychotic activity in vivo.