206873-11-2

Upstream product

• 873695-04-6 C₁₈H₂₅NO₄S 
• 18303-04-3 N-[(tert-butoxy)carbonyl]-4-methylbenzenesulfonamide 
• 17102-64-6 Sorbyl alcohol 
• 70-55-3 toluene-4-sulfonamide 

Downstream Products

• 1152437-70-1 N,N'-(4-methylpenta-2,3-dien-1-yl)[(2E,4E)-5-penta-2,4-dien-1-yl]-N-toluenesulfonamide 
• 873694-87-2 N-(3-bromoprop-2-ynyl)-N-hexa-2,4-dienyl-4-methylbenzenesulfonamide 
• 452915-40-1 N-[(2E,4E)-hexa-2,4-dien-1-yl]-4-methyl-N-(prop-2-yn-1-yl)benzenesulfonamide 

Relevant academic research and scientific papers

Rhodium-catalyzed intramolecular [4 + 2] cycloadditions of alkynyl halides

(Chemical Equation Presented) Cationic rhodium(I)-catalyzed intramolecular [4 + 2] cycloadditions of diene-tethered alkynyl halides were found to occur in good yields (70-87%). The halide moiety is compatible with the cycloaddition reactions, and no oxidative insertion to the alkynyl halide was observed. The halogen-containing cycloadducts could be transformed into a variety of products that are difficult or impossible to obtain via direct cycloaddition.

Alkynyliodonium salts in organic synthesis. Preparation of annelated dihydropyrroles by cascade addition/bicyclization of dienyltosylamide anions with phenyl(propynyl)iodonium triflate

The addition of simple pentadienyltosylamide derivatives to the two- carbon electrophile phenyl(propynyl)iodonium triflate initiates a sequence of transformations that furnishes complex, highly functionalized cyclopentenannelated dihydropyrrole products in moderate yields with complete stereoselection. This sequence demonstrates that diyls resulting from homolytic scission of alkylidene carbene-alkene adducts can be readily accessed under mild experimental conditions and that, in the presence of appropriate pendant functionality, these diyls can productively cyclize. The isomeric isoprene-derived tosylamides follow an abbreviated reaction course and deliver azabicyclo[3.1.0]hexanes via an isomerization that competes with diyl formation.