206879-65-4

Basic information

• Product Name: 1-[4-(3-AMINOPHENYL)PIPERAZIN-1-YL]ETHANONE
• Synonyms: 1-[4-(3-AMINOPHENYL)PIPERAZIN-1-YL]ETHANONE;3-(4-Acetyl-piperazin-1-yl)aniline
• CAS NO: 206879-65-4
• Molecular Formula: C₁₂H₁₇N₃O
• Molecular Weight: 219.28
• Mol File: 206879-65-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 127-129 °C
• Boiling Point: 462.414 °C at 760 mmHg
• Flash Point: 233.46 °C
• Appearance: /
• Density: 1.177 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.597
• PKA: 5.35±0.10(Predicted)
• CAS DataBase Reference: 1-[4-(3-AMINOPHENYL)PIPERAZIN-1-YL]ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(3-AMINOPHENYL)PIPERAZIN-1-YL]ETHANONE(206879-65-4)
• EPA Substance Registry System: 1-[4-(3-AMINOPHENYL)PIPERAZIN-1-YL]ETHANONE(206879-65-4)

Safety Data

• Hazardous Substances Data: 206879-65-4(Hazardous Substances Data)

Usage

General Description

The chemical "1-[4-(3-aminophenyl)piperazin-1-yl]ethanone" is a compound with the molecular formula C13H18N2O. It is a ketone derivative and contains a piperazine ring with an amino group and a phenyl ring. 1-[4-(3-AMINOPHENYL)PIPERAZIN-1-YL]ETHANONE has potential applications in medicinal chemistry and pharmaceutical research due to its ability to interact with receptors and enzymes in the body. It may also have implications in the development of new therapeutic agents for various medical conditions. However, further research is needed to fully understand its specific properties and potential uses.

InChI:InChI=1/C12H17N3O/c1-10(16)14-5-7-15(8-6-14)12-4-2-3-11(13)9-12/h2-4,9H,5-8,13H2,1H3

Upstream product

• 123207-57-8 3-(N-Morpholinomethyl)-1-nitrobenzene 
• 294210-79-0 1-(3-nitrophenyl)piperazine monohydrochloride 
• 99-09-2 3-nitro-aniline 
• 314061-17-1 1-acetyl-4-(3-nitrophenyl)piperazine 

Downstream Products

• 913365-80-7 1-{4-[3-(4-methyl-2-nitro-phenylamino)-phenyl]-piperazin-1-yl}-ethanone 
• 913365-84-1 1-{4-[3-(2-amino-4-methyl-phenylamino)-phenyl]-piperazin-1-yl}-ethanone 
• 1023276-40-5 2-[3-(4-acetyl-piperazin-1-yl)-phenylamino]-8-indan-5-yl-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid methoxy-amide 
• 913365-83-0 1-{4-[3-(4-methoxy-2-nitro-phenylamino)-phenyl]-piperazin-1-yl}-ethanone 
• 913365-79-4 N-[3-(4-acetyl-piperazin-1-yl)-phenyl]-formamide 
• 314061-54-6 Ethyl 4-(3-(4-acetyl-1-piperazinyl)-phenyl)-amino-6-fluoro-3-nitrobenzoate 
• 766504-41-0 N-{3-[4-(3-benzo[b]thiophen-3-yl-3-oxo-propyl)-piperazin-1-yl]-phenyl}-methanesulfonamide 
• 500882-30-4 1-(3-methanosulphonamidephenyl)piperazine 

Relevant articles and documents

Benzimidazole derivatives and their use for modulating the gaba-alpha receptor complex

This invention relates to novel benzimidazole derivatives, pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disord

BENZIMIDAZOLE DERIVATIVES AND THEIR USE FOR MODULATING THE GABAA RECEPTOR COMPLEX

This invention relates to novel benzimidazole derivatives, pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABAA receptor complex, and in particular for combating anxiety and related diseases.

New 3-[4-(3-substituted phenyl)piperazin-1-yl]-1-(benzo[b]thiophen-3-yl)-propanol derivatives with dual action at 5-HT1A serotonin receptors and serotonin transporter as a new class of antidepressants

In this paper a series of new 3-[4-(3-substituted phenyl)piperazin-1-yl]-1-(benzo[b]thiophen-3-yl)propanol derivatives is presented as a new class of antidepressant drugs with dual activity at 5-HT1A serotonin receptors and serotonin transporte