500882-30-4

Upstream product

• 900800-89-7 1-[3-methylsulfonylaminophenyl]-4-tert-butoxycarbonyl-piperazine 
• 294210-79-0 1-(3-nitrophenyl)piperazine monohydrochloride 
• 99-09-2 3-nitro-aniline 
• 314061-17-1 1-acetyl-4-(3-nitrophenyl)piperazine 
• 206879-65-4 1-(4-(3-aminophenyl)piperazin-1-yl)ethanone 

Downstream Products

• 900800-71-7 N-[4-(4-(3-methylsulfamidophenyl)piperazin-1-yl)butyl]-3,4-dihydro-2-naphthamide 
• 766504-41-0 N-{3-[4-(3-benzo[b]thiophen-3-yl-3-oxo-propyl)-piperazin-1-yl]-phenyl}-methanesulfonamide 

Relevant academic research and scientific papers

3,4-dihydro-2-naphthamide derivatives as selective dopamine D3 ligands

The invention relates to 3,4-dihydro-2-naphthamide derivatives of formula (I), pharmaceutical compositions containing them and their therapeutic applications as partial agonists or antagonists of the dopamine D3 receptor for the treatment of neuropsychological disorders.

New 3-[4-(3-substituted phenyl)piperazin-1-yl]-1-(benzo[b]thiophen-3-yl)-propanol derivatives with dual action at 5-HT1A serotonin receptors and serotonin transporter as a new class of antidepressants

In this paper a series of new 3-[4-(3-substituted phenyl)piperazin-1-yl]-1-(benzo[b]thiophen-3-yl)propanol derivatives is presented as a new class of antidepressant drugs with dual activity at 5-HT1A serotonin receptors and serotonin transporte