206991-15-3

Upstream product

• 206991-19-7 {3-[2,6-Dibromo-4-(2-tert-butoxycarbonylamino-ethyl)-phenoxy]-propyl}-carbamic acid benzyl ester 
• 206991-18-6 (3-{2,6-Dibromo-4-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethyl]-phenoxy}-propyl)-carbamic acid benzyl ester 
• 206991-17-5 N-phthaloyl-2-(3,5-dibromo-4-hydroxyphenyl)ethylamine 
• 134755-34-3 3,5-dibromo-4-hydroxy-β-phenethylamine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 206991-20-0 {2-[4-(3-{3-(2-Benzyloxy-3,5-dibromo-4-methoxy-phenyl)-2-[(Z)-hydroxyimino]-propionylamino}-propoxy)-3,5-dibromo-phenyl]-ethyl}-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Studies on synthesis of araplysillins via oxidative cyclisation of o-phenolic oxime-acid derivatives using phenyliodonium diacetate

Efficient synthetic approaches of cyclohexadienonespiroisoxazoline-amides (1), which could be useful as intermediates for the synthesis of dibromotyrosine derived marine natural products araplysillins, are described. Direct cyclisation of o-phenolic oxime-amide (5) with phenyliodonium diacetate (PIDA) produced 1. Amidation of cyclohexadienonespiroisoxazoline-acid (6) also took place efficiently to afford 1.