134755-34-3Relevant academic research and scientific papers
Synthesis and absolute configuration of acanthodendrilline, a new cytotoxic bromotyrosine alkaloid from the Thai marine sponge acanthodendrilla sp.
Sirimangkalakitti, Nachanun,Yokoya, Masashi,Chamni, Supakarn,Chanvorachote, Pithi,Plubrukrn, Anuchit,Saito, Naoki,Suwanborirux, Khanit
, p. 258 - 262 (2016)
Acanthodendrilline (1), a new bromotyrosine alkaloid, was isolated from the Thai marine sponge Acanthodendrilla sp. The structure of 1 was fully characterized by spectroscopic analysis, in agreement with the synthesized compound used to resolve the single
Total Synthesis of Enisorine D and its Analogues
Hussain, Mulla Althafh,Khan, Faiz Ahmed,Shashi, Shashi
, p. 4601 - 4610 (2019)
The first total synthesis of enisorine D, a natural product isolated from the marine sponge Iotrochota cf. iota, is described in 64percent overall yield. The target molecule, which is an inhibitor of T3SS-dependent Yope secretion of Y. pseudotuberculosis, is achieved in seven linear steps from tyramine via simple and effective transformations that include bromination, acylation, alkylation, azidation, reduction and routine acid-amine coupling. A total of sixteen analogues are prepared by coupling with eight different cinnamic acids, two bromopyrrole carboxylic acids, five phenyl carboxylic acids and picolinic acid.
Structural activity relationship studies of zebra mussel antifouling and antimicrobial agents from verongid sponges
Diers, Jeffrey A.,Pennaka, Hari Kishore,Peng, Jiangnan,Bowling, John J.,Duke, Stephen O.,Hamann, Mark T.
, p. 2117 - 2120 (2004)
Several dibromotyramine derivatives including moloka'iamine were selected as potential zebra mussel (Dreissena polymorpha) antifoulants due to the noteworthy absence of fouling observed on sponges of the order Verongida. Sponges of the order Verongida con
Synthesis of purpuroine A, nakirodin A and MDN-0104: The hidden puzzles and risk of error in their configurational assignments
Wu, Wen-Ju,Wu, Yikang,Liu, Bo
, p. 1265 - 1274 (2017/02/10)
The unusual (R) configuration previously assigned (with seemingly undoubted evidence) to purpuroin A and nakirodin A was disproved by synthesis. The optical rotation and NMR data for structure assigned for salt-free nakirodin A were made available for the
DIBENZENE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS
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Page/Page column 14, (2009/04/24)
The invention is directed to a compound of formula (I) Having VDCC blocking activity. These compounds are useful for the treatment of a series of human diseases and conditions, especially cognitive or neurodegenerative diseases or conditions.
