206991-72-2Relevant academic research and scientific papers
Synthesis and evaluation of unsymmetrical polyamine derivatives as antitumor agents
Wang, Jianhong,Xie, Songqiang,Li, Yanjie,Guo, Yongjun,Ma, Yuanfang,Zhao, Jin,Phanstiel IV, Otto,Wang, Chaojie
, p. 7005 - 7012 (2008/12/22)
A series of unsymmetrically substituted polyamine derivatives were prepared and their cytotoxicities in mouse leukemia L1210, melanoma B16, and HeLa cells were investigated. The in vitro cytotoxicity revealed that these conjugates could recognize the poly
Synthesis and evaluation of hydroxylated polyamine analogues as antiproliferatives
Bergeron,Müller,Huang,McManis,Algee,Yao,Weimar,Wiegand
, p. 2451 - 2459 (2007/10/03)
A new means of accessing N1-cyclopropylmethyl-N11-ethylnorspermine (CPMENSPM) and the first synthesis of (2R,10S)-N1- cyclopropylmethyl-2,10-dihydroxy-N11-ethylnorspermine [(2R,10S)-(HO)2CPMENSPM] are
Conformationally restricted analogues of 1N,12N-bisethylspermine: Synthesis and growth inhibitory effects on human tumor cell lines
Reddy, Venodhar K.,Valasinas, Aldonia,Sarkar, Aparajita,Basu, Hirak S.,Marton, Laurence J.,Frydman, Benjamin
, p. 4723 - 4732 (2007/10/03)
Eight analogues of 1N, 12N-bisethylspermine (BES) with restricted conformations were synthesized in the search for new spermine mimetics with cytotoxic activities. By replacing the central butane segment of BES with a 1,2-disubstitut
