151915-15-0Relevant articles and documents
Synthesis and evaluation of hydroxylated polyamine analogues as antiproliferatives
Bergeron,Müller,Huang,McManis,Algee,Yao,Weimar,Wiegand
, p. 2451 - 2459 (2007/10/03)
A new means of accessing N1-cyclopropylmethyl-N11-ethylnorspermine (CPMENSPM) and the first synthesis of (2R,10S)-N1- cyclopropylmethyl-2,10-dihydroxy-N11-ethylnorspermine [(2R,10S)-(HO)2CPMENSPM] are
Synthesis and evaluation of unsymmetrically substituted polyamine analogues as modulators of human spermidine/spermine-N1-acetyltransferase (SSAT) and as potential antitumor agents
Saab,West,Bieszk,Preuss,Mank,Casero Jr.,Woster
, p. 2998 - 3004 (2007/10/02)
Spermidine/spermine-N1-acetyltranferase (SSAT), the rate-limiting step in polyamine catabolism, is critical for the interconversion and modulation of cellular polyamines. Inhibitor-initiated induction of this enzyme also appears to correlate wi