206998-33-6

Basic information

• Product Name: Benzoic acid (E)-(S)-6-ethoxycarbonyl-1-ethynyl-4-methyl-hept-5-enyl ester
• CAS NO: 206998-33-6
• Molecular Weight: 328.408
• Mol File: 206998-33-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzoic acid (E)-(S)-6-ethoxycarbonyl-1-ethynyl-4-methyl-hept-5-enyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid (E)-(S)-6-ethoxycarbonyl-1-ethynyl-4-methyl-hept-5-enyl ester(206998-33-6)
• EPA Substance Registry System: Benzoic acid (E)-(S)-6-ethoxycarbonyl-1-ethynyl-4-methyl-hept-5-enyl ester(206998-33-6)

Safety Data

• Hazardous Substances Data: 206998-33-6(Hazardous Substances Data)

Upstream product

• 206998-30-3 Benzoic acid (S)-4-methyl-5-(tetrahydro-pyran-2-yloxy)-1-trimethylsilanylethynyl-pentyl ester 
• 206998-29-0 Benzoic acid (S)-1-ethynyl-4-methyl-5-(tetrahydro-pyran-2-yloxy)-pentyl ester 
• 206998-31-4 Benzoic acid (S)-1-ethynyl-5-hydroxy-4-methyl-pentyl ester 
• 206998-27-8 (S)-6-Methyl-7-(tetrahydro-pyran-2-yloxy)-1-trimethylsilanyl-hept-1-yn-3-ol 
• 206998-23-4 (E)-(S)-4-Methyl-5-(tetrahydro-pyran-2-yloxy)-pent-2-enoic acid methyl ester 
• 206998-24-5 (S)-4-Methyl-5-(tetrahydro-pyran-2-yloxy)-pentanoic acid methyl ester 
• 206998-28-9 (S)-6-Methyl-7-(tetrahydro-pyran-2-yloxy)-hept-1-yn-3-ol 
• 206998-26-7 (S)-4-Methyl-5-(tetrahydro-pyran-2-yloxy)-pentanal 
• 206998-25-6 (S)-4-Methyl-5-(tetrahydro-pyran-2-yloxy)-pentan-1-ol 
• 21382-82-1 (carbethoxyethylidene)triphenylphosphorane 
• 206998-32-5 Benzoic acid (S)-1-ethynyl-4-methyl-5-oxo-pentyl ester 

Relevant articles and documents

Stille coupling reactions in the preparation of substituted trienic systems

The formation of the tetraenoate 2 was envisaged during a synthetic approach to the decalin system 1. The iododiene 3 was obtained in high yield from the corresponding stannyl derivative. The right hand fragment 13a was synthesized from propionate 8 using, during this sequence, a condensation of (E)-1-lithio-2-tributylstannylethene with aldehyde 10. The Pd(0)-catalyzed Stille coupling reaction between 3 and 13a was then realized in 75% yield to deliver the expected triene 23 which was then transformed into the expected tetraenoate 2.