207-83-0

Usage

Carcinogenicity

In two bioassays in which mice received repeated dermal applications 13H-dibenzo[a,g] fluorene yielded positive results, although control groups were not included for comparison.

InChI:InChI=1/C21H14/c1-3-7-17-14(5-1)11-12-19-20(17)13-16-10-9-15-6-2-4-8-18(15)21(16)19/h1-12H,13H2

Upstream product

• 55723-90-5 2-[1]naphthylmethyl-3,4-dihydro-2H-naphthalen-1-one 
• 55723-89-2 2-(2-naphthyl)methylidene-3,4-dihydro-2H-naphthalen-1-one 
• 263714-30-3 1-(naphthalene-2-ylmethyl)-3,4-dihydronaphthalene-2(1H)-one 
• 106031-71-4 13H-Dibenzo[a,g]fluorene-13-carboxylic acid ethyl ester 
• 186407-93-2 naphthalen-1-yl(naphthalen-2-yl)methanol 
• 55723-88-1 (E)-2-(2-naphthyl)methylidene-3,4-dihydro-2H-naphthalen-1-one 
• 56-23-5 tetrachloromethane 
• 55760-09-3 (E)-3,4-dihydro-2-((naphthalen-1-yl)methylene)naphthalen-1(2H)-one 
• 530-93-8 1,2,3,4-tetrahydronaphthalen-2-one 
• 939-26-4 2-bromomethylnaphthyl bromide 
• 94307-49-0 3-[2]naphthyl-2-phenyl-acrylic acid 
• 66-99-9 β-naphthaldehyde 
• 100146-00-7 <2-Phenyl-4,5-benzindenyl-(3)>-essigsaeure 
• 100575-63-1 3,4-Dihydro-3-oxo-1,2:5,6-dibenzofluoren 

Downstream Products

• 63041-47-4 13H-dibenzofluoren-13-one 
• 488829-89-6 (13H-dibenzo[a,g]fluoren-11-ylmethylene)-phenyl-amine 

Relevant academic research and scientific papers

An expeditious one pot synthesis of dibenzo[a,g]fluorene

A convenient one-pot synthesis of dibenzo[a,g]fluorene via enolate alkylation and cyclodehydration-aromatisation route has been developed.

AMINODIBENZOFLUORENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME

A novel compound which is useful as a constitutional component for an organic EL device is provided by an aminodibenzofluorene derivative comprising (A) at least one dibenzofluorene structure and (B) at least one amino group in a molecule, a material for an organic electroluminescence (EL) device comprising the same, a light emitting material for an organic EL device, a light emitting organic solution, an organic EL device in which an organic compound layer comprising a single layer or plural layers including at least a light emitting layer is interposed between a pair of electrodes, wherein at leas one layer in the organic compound layer described above contains at least one kind of the aminodibenzofluorene derivative described above and an equipment comprising the same. A practical organic EL device which has a low operating voltage, a long lifetime and a high current efficiency and which provides blue light emission having an excellent color purity is materialized by using the above compound.

Stereocontrolled synthesis of anticancer β-lactams via the Staudinger reaction

Stereocontrolled synthesis of novel β-lactams using polyaromatic imines following the Staudinger reaction has been accomplished. The effects of domestic microwave irradiation on this type of reaction have been investigated. Formation of trans-β-lactams has been explained through isomerization of the enolates formed during the reaction of acid chloride (equivalent) with imines in the presence of triethylamine. A donor-acceptor complex pathway is believed to be involved in the formation of cis-β-lactams. The effect of a peri hydrogen has been found to be significant in controlling the stereochemistry of the resulting β-lactams. SAR has identified β-lactams with anticancer activity. The presence of an acetoxy group has proven obligatory for their anticancer activity.

A New General Synthesis of Polycyclic Aromatic Compounds Based on Enamine Chemistry

Alkylation of enamines and enamine salts by benzylic and (β-haloethyl)aryl halides, respectively, followed by acidic cyclodehydration and dehydrogenation provides an efficient synthetic approach to a wide range of polycyclic aromatic compounds of diverse structural types.Specific polycyclic hydrocarbons synthesized by this route include benzo- and benzofluorene, 7H-dibenzo-, 13H-dibenzo-, and 13H-dibenzofluorene, 15H-tribenzofluorene, dibenzochrysene, benzopentaphene, indenofluorene, fluorenofluorene, octahydrodibenzanthracene, dibenzanthracene, octahydrodibenzanthracene, dibenzanthracene, picene, benzopicene, 1H-benzaceanthrylene, and 4H-cyclopentachrysene.This method with appropriate modifications appears to be potentially broader in scope than established traditional methods of polycyclic hydrocarbon synthesis.

An Efficient Synthesis of Benzofluorenes Via α-Alkoxycarbonyldiarylmethyl Cations

Rearrangement of α-alkoxycarbonyldiarylmethyl cations lead to 9-fluorenecarboxylic esters.Decarboxylation of these esters generates the fluorene derivatives 9a-f.The precursors to the cations are the α-hydroxyesters 6a-g.This conversion constitutes a facile synthesis of benzofluorenes.