20715-27-9Relevant academic research and scientific papers
Total synthesis of 8-methoxygoniodiol related compounds via chiron approach
Yadav, Jhillu Singh,Madhava Rao, Batta,Sanjeeva Rao, Kodepelly
experimental part, p. 1725 - 1730 (2009/12/24)
The stereoselective synthesis of 8-methoxygoniodiol related compounds was accomplished by using readily available δ-gluconolactone as a chiral source. The stereoselective addition of an aryl Grignard reagent on an aldehyde, stereoselective reduction of a keto group and regioselective opening of a chiral epoxide by ethyl propiolate are the key steps involved in this synthesis.
