207277-37-0Relevant academic research and scientific papers
Substituted phenoxyalkylpiperazines as dopamine d3 receptor ligands
Laszlovszky,Acs,Kiss,Domany
, p. 287 - 289 (2007/10/03)
A novel series of potential antipsychotic agents were prepared by combination of condensed heterocycles containing bridgehead nitrogen with (2-methoxyphenyl)piperazine using phenoxyalkyl spacer of variable length. The affinity of the compounds was determined at rat cloned D3 and rat D2, 5-HT1A receptors by an vitro receptor binding assay. The D3 selectivity of the compounds was calculated from the Ki values.
