207278-54-4Relevant academic research and scientific papers
Synthesis and pharmacological evaluation of novel cis-3,4-Diaryl-hydroxychromanes as high affinity partial agonists for the estrogen receptor
Bury, Paul S.,Christiansen, Lise B.,Jacobsen, Poul,Jorgensen, Anker S.,Kanstrup, Anders,Narum, Lars,Bain, Steven,Fledelius, Christian,Gissel, Birgitte,Hansen, Birgit S.,Korsgaard, Niels,Thorpe, Susan M.,Wassermann, Karsten
, p. 125 - 145 (2007/10/03)
The syntheses and in vitro pharmacological evaluation of a number of cis-3,4-diaryl-hydroxy-chromanes are reported, along with the results of a thorough in vivo profiling of the tissue-selective estrogen partial-agonist NNC 45-0781 [3, (-)-(3S,4R)-7-hydro
cis3, 4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
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, (2008/06/13)
The present invention relates to therapeutically active compounds of formula I a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the prevention or treatment of estrogen related diseases or syndromes.
Trans-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
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, (2008/06/13)
The present invention relates to therapeutically active compounds of formula I STR1 a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the prevention or treatment of estrogen relat
