207279-92-3

Upstream product

• 207279-90-1 6,7-Bis-benzyloxy-2,3-dihydro-[1,4]naphthoquinone 
• 74-88-4 methyl iodide 

Downstream Products

• 1027937-03-6 3-[(Z)-6-(tert-Butyl-diphenyl-silanyloxy)-4-methyl-hex-4-enyl]-5,8-dimethoxy-naphthalen-2-ol 
• 191352-89-3 tert-Butyl-[(E)-2-(5,8-dimethoxy-1-methyl-1,2,3,4-tetrahydro-anthracen-1-yl)-vinyloxy]-diphenyl-silane 
• 179469-95-5 tert-Butyl-[(E)-2-((S)-5,8-dimethoxy-1-methyl-1,2,3,4-tetrahydro-anthracen-1-yl)-vinyloxy]-diphenyl-silane 
• 179469-94-4 Trifluoro-methanesulfonic acid 3-[(Z)-6-(tert-butyl-diphenyl-silanyloxy)-4-methyl-hex-4-enyl]-5,8-dimethoxy-naphthalen-2-yl ester 

Relevant academic research and scientific papers

Catalytic asymmetric synthesis of halenaquinone and halenaquinol

A catalytic asymmetric synthesis of halenaquinone (1) and halenaquinol (2) has been achieved using an asymmetric Heck reaction or a cascade Suzuki cross-coupling and an asymmetric Heck reaction as a key step. This synthesis also features the one-pot construction of a unique pentacyclic ring system from a tricyclic system using palladium chemistry. Moreover, the use of Ph3As as an achiral ligand has been found to enhance both the cascade Suzuki cross-coupling and also the Heck reaction to a synthetically useful extent.