207286-83-7

Upstream product

• 207286-81-5 Ethyl 3-(4-bromophenyl)-2-[[hydroxy[2-phenyl-1-[[(phenylmethoxy)carbonyl]amino]ethyl]phosphinyl]methyl]propanoate 
• 207286-80-4 ethyl 4-bromo-α-methylenebenzenepropanoate 
• 207286-82-6 ethyl 3-[1,1'-biphenyl]-4-yl-2-[[hydroxy[2-phenyl-1-[[(phenylmethoxy)carbonyl]amino]ethyl]phosphinyl]methyl]propanoate 
• 115961-49-4 [2-phenyl-1-[[(phenylmethoxy)carbonyl]amino]ethyl]phosphinic acid 
• 894778-85-9 2-[(adamantan-1-yloxy)-(1-benzyloxycarbonylamino-2-phenyl-ethyl)-phosphinoylmethyl]-malonic acid diethyl ester 
• 894778-80-4 (RS)-2-[(1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoylmethyl]-malonic acid diethyl ester 
• 894778-93-9 (RS)-2-[(1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoylmethyl]-2-biphenyl-4-ylmethyl-malonic acid diethyl ester 

Downstream Products

• 207286-84-8 methyl N-[3-[1,1'-biphenyl]-4-yl-2-[[hydroxy[2-phenyl-1-[[(phenylmethoxy)carbonyl]amino]ethyl]phosphinyl]methyl]-1-oxopropyl]-L-alaninate 
• 268225-39-4 (S)-2-{3-[(1-Benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-2-biphenyl-4-ylmethyl-propionylamino}-4-methyl-pentanoic acid 
• 268225-38-3 (S)-2-{3-[(1-Benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-2-biphenyl-4-ylmethyl-propionylamino}-butyric acid 
• 207286-85-9 N-[3-[1,1'-biphenyl]-4-yl-2-[[hydroxy[2-phenyl-1-[[(phenylmethoxy)carbonyl]amino]ethyl]phosphinyl]methyl]-1-oxopropyl]-L-alanine 

Relevant academic research and scientific papers

Active methylene phosphinic peptides: A new diversification approach

Simple, rapid, and efficient methods for P1′ diversification of phosphinic peptides have been developed, employing alkylation and Knoevenagel-type condensation reactions with active methylene phosphinic scaffolds, thus leading to a wide variety

Phosphinic derivatives as new dual enkephalin-degrading enzyme inhibitors: Synthesis, biological properties, and antinociceptive activities

The development of dual inhibitors of the two zinc metallopeptidases, neprilysin (neutral endopeptidase) and aminopeptidase N involved in the inactivation of the opioid peptides, enkephalins, represents an attractive physiological approach in the search f