207347-40-8Relevant articles and documents
Structurally altered substrates for DNA topoisomerase I. Effects of inclusion of a single 3'-deoxynucleotide within the scissile strand
Arslan, Tuncer,Abraham, Anil T.,Hecht, Sidney M.
, p. 515 - 530 (2007/10/03)
A partial DNA duplex containing a high efficiency topoisomerase I cleavage site was substituted singly at each of three sites with 3'- deoxyadenosine. Depending on the site of substitution, the facility of the topoisomerase I-mediated cleavage or ligation