76902-49-3

Upstream product

• 66884-45-5 (2R,3R,5S)-2-[6-(N-benzoylbenzamido)-9H-purin-9-yl]-5-[(benzoyloxy)methyl]oxolan-3-yl benzoate 
• 77244-85-0 2'-O-acetyl-N⁶-benzoyl-3'-deoxyadenosine 
• 4546-55-8 N-benzoyladenosine 
• 73-03-0 cordycepin 
• 98-88-4 benzoyl chloride 
• 144867-90-3 2,2-dimethylpropionic acid 2,3-dihydrofuran-2-ylmethyl ester 
• 207347-40-8 Acetic acid (2R,3R,5S)-2-(6-benzoylamino-purin-9-yl)-5-((R)-1,2-diacetoxy-ethyl)-tetrahydro-furan-3-yl ester 
• 60855-35-8 6-benzoylamino-9-trimethylsilylpurine 
• 58-61-7 adenosine 
• 329014-11-1 9-(2'-O-acetyl-3'-bromo-5'-O-tert-butyldiphenylsilyl-3'-deoxy-β-D-xylofuranosyl)-6-N-benzoyl adenine 
• 80615-03-8 Acetic acid (2R,3R,5S)-2-(6-benzoylamino-purin-9-yl)-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-3-yl ester 
• 118684-36-9 O^2;_,O3'_,O5'-tris-trimethylsilyl-N⁶-benzoyladenosine 
• 77244-83-8 6-N-benzoyl-9-(5-O-tert-butyldiphenylsilyl-β-D-ribofuranosyl)adenine 
• 10457-15-5 O^2'_,O3'_,O5'-tris-trimethylsilanyl-adenosine 

Downstream Products

• 84138-86-3 N-(9-((2R,3R,5S)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-hydroxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide 
• 76885-92-2 N⁶-benzoyl-3'-deoxy-5'-O-(monomethoxytrityl)adenosine 
• 220867-47-0 N⁶-benzoyl-3'-deoxy-5'-O-<(p-toluyl)sulfonyl>adenosine 
• 220867-48-1 5'-azido-N⁶-benzoyl-3',5'-dideoxyadenosine 
• 220867-49-2 3',5'-dideoxy-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>-5'-<<2-(4-nitrophenyl)ethoxycarbonyl>amino>adenosine 
• 220867-54-9 3',5'-dideoxy-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>-5'-<<2-(4-nitrophenyl)ethoxycarbonyl>amino>adenosine 2'-O-<2-cyanoethyl diisopropylphosphoramidite> 
• 76885-95-5 Phosphoric acid (2R,3R,5S)-2-(6-benzoylamino-purin-9-yl)-5-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester; compound with triethyl-amine 
• 76902-50-6 Phosphoric acid (2R,3R,5S)-2-(6-benzoylamino-purin-9-yl)-5-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester 2-cyano-ethyl ester 
• 76885-96-6 Phosphoric acid (2R,3R,5S)-2-(6-benzoylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester 2-cyano-ethyl ester 
• 138824-83-6 Benzoic acid (2R,3R,5S)-5-[[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethoxy]-(2-cyano-ethoxy)-phosphanyloxymethyl]-2-(6-benzoylamino-purin-9-yl)-tetrahydro-furan-3-yl ester 
• 138800-30-3 N⁶,O^2'-dibenzoyl-5'-(dimethoxytrityl)-3'-deoxyadenosine 
• 128893-74-3 N⁶,O^2'-dibenzoyl-3'-deoxyadenosine 
• 115196-56-0 N⁶-benzoyl-3'-deoxyadenylyl-<2'-P-2-(p-nitrophenyl)ethyl)>-> 5'>-N⁶-benzoyl-2'-O-<(tert-butyldimethyl)silyl>-3'-deoxyadenosine 

Relevant academic research and scientific papers

CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS

A class of polycyclic compounds of general formula (II), of general formula (II'), or of general formula (II"), wherein Base1, Base2, Y, Ya, Xa, Xa1, Xb, Xb1, Xc, Xsu

Efficient synthesis of protected 3′-deoxyadenosine and 3′-deoxyguanosine from adenosine and guanosine

Highly efficient synthesis of protected 3′-deoxyadenosine and 3′-deoxyguanosine from adenosine and guanosine were described. The 2′,3′-diol of protected adenosine and guanosine were reacted with α-acetoxyisobutyryl bromide to yield 9-(2′-O-acetyl-3′-bromo

Structurally altered substrates for DNA topoisomerase I. Effects of inclusion of a single 3'-deoxynucleotide within the scissile strand

A partial DNA duplex containing a high efficiency topoisomerase I cleavage site was substituted singly at each of three sites with 3'- deoxyadenosine. Depending on the site of substitution, the facility of the topoisomerase I-mediated cleavage or ligation

Asymmetric synthesis of nucleosides via molybdenum-catalyzed alkynol cycloisomerization coupled with stereoselective glycosylations of deoxyfuranose glycals and 3-amidofuranose glycals

Deoxygenated furanose glycals were efficiently prepared by molybdenum pentacarbonyl-catalyzed cycloisomerization of alkynyl alcohols, which were easily prepared in chiral nonracemic form by short synthetic sequences featuring asymmetric epoxidations of commercially available allylic alcohols. The cycloisomerization reaction was demonstrated to be compatible with ester and amide functional groups. A 2,3-dideoxyfuranose glycal was stereoselectively converted into the anti-AIDS β-nucleoside stavudine (2',3'-didehydro-2',3'-dideoxythymidine, d4T) and the antiviral 3'-deoxy-β-nucleoside cordycepin. The anchimeric and hydrogen-bond-directing effects of 3-amido-2,3-dideoxyfuranose glycals were exploited in a novel and highly stereoselective synthesis strategy for a variety of biologically active 3'-amino-2',3'-dideoxy- and 3'-amino-3'-deoxy-β-nucleosides, including puromycin aminonucleoside. In addition, the mechanism of the molybdenum-catalyzed alkynol cycloisomerization reaction has been studied. Evidence is presented which indicates that cyclic molybdenum carbene anions are catalytic intermediates in these cyclizations.

SYNTHESIS AND PROPERTIES OF 3'-DEOXYADENYLATE TRIMER dA2'p5'A2'P5'A

The trimeric 3'-deoxyadenylyl-(2'->5')-3'-deoxyadenylyl-(2'->5')-3'-deoxyadenosine (12) was synthesized via the phosphotriester approach starting from cordycepine (1).Various physical data have been determined and compared with those of the ribo-A2'p5'A2'p5'A analog.