20736-09-8

Basic information

• Product Name: Saikosaponin A
• Synonyms: SAIKOSAPONIN A(RG);dihydroxyolean-11-en-3-yl6-deoxy-3-O-β-D-;β-D-fucoside, (3β,4α,16β)-13,28-epoxy-16,23-;[(3β,4R)-13,28-Epoxy-16β,23-dihydroxyolean-11-en-3-yl]3-O-(β-D-glucopyranosyl)-6-deoxy-β-D-galactopyranoside;[(4R)-13,28-Epoxy-16β,23-dihydroxyolean-11-en-3β-yl]3-O-(β-D-glucopyranosyl)-6-deoxy-β-D-galactopyranoside;SABINYL ACETATE(RG);Thesaikosaponin A;SAIKOSAPONIN A
• CAS NO: 20736-09-8
• Molecular Formula: C₄₂H₆₈O₁₃
• Molecular Weight: 780.98
• EINECS: 244-001-6
• Product Categories: Saponins;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors
• Mol File: 20736-09-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 225～232℃ (dec.)
• Boiling Point: 893.675 °C at 760 mmHg
• Flash Point: 494.277 °C
• Appearance: White crystalline powder
• Density: 1.36 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.616
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly, Sonicated), Pyridine (Slightly)
• PKA: 12.83±0.70(Predicted)
• Stability: Hygroscopic
• CAS DataBase Reference: Saikosaponin A(CAS DataBase Reference)
• NIST Chemistry Reference: Saikosaponin A(20736-09-8)
• EPA Substance Registry System: Saikosaponin A(20736-09-8)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 20736-09-8(Hazardous Substances Data)

Usage

Uses

Saikosaponin A was shown to exhibit anti-inflammatory activities by suppressing activation of NF-kB signaling pathway.

InChI:InChI=1/C42H68O13/c1-21-28(46)33(55-34-31(49)30(48)29(47)22(18-43)53-34)32(50)35(52-21)54-27-10-11-37(4)23(38(27,5)19-44)8-12-39(6)24(37)9-13-42-25-16-36(2,3)14-15-41(25,20-51-42)26(45)17-40(39,42)7/h9,13,21-35,43-50H,8,10-12,14-20H2,1-7H3/t21-,22-,23-,24-,25-,26+,27+,28+,29-,30+,31-,32-,33+,34+,35+,37+,38+,39-,40+,41-,42+/m1/s1

Upstream product

• 102934-42-9 2-O-acetylsaikosaponin a 
• 58316-43-1 C₅₈H₈₄O₂₁ 
• 58316-43-1 saikosaponin-a octaacetate 

Downstream Products

• 99365-19-2 3-O-β-D-glucopyranosyl-(1->3)-β-D-fucopyranosyl 3β,16β,23,28-tetrahydroxyolean-9(11),12(13)-diene 
• 58558-08-0 saikosaponin B₁ 
• 99365-23-8 prosaikogenin F 

Relevant articles and documents

Chemical evaluation of Bupleurum species collected in Yunnan, China

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Isolation, characterization, and nuclear magnetic resonance spectra of new saponins from the roots of Bupleurum falcatum L.

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