2074-83-1Relevant academic research and scientific papers
Nickel-catalyzed three-component domino reactions of aryl grignard reagents, alkynes, and aryl halides producing tetrasubstituted alkenes
Xue, Fei,Zhao, Jin,Hor, T. S. Andy,Hayashi, Tamio
, p. 3189 - 3192 (2015)
Three-component reaction of aryl Grignard reagents, alkynes, and aryl halides in the presence of 1 mol % of NiCl2 proceeded sequentially through carbomagnesiation of the alkyne followed by cross-coupling of the resulting alkenyl Grignard reagent with aryl halide to give tetrasubstituted alkenes in high yields.
