2075-22-1

Basic information

• Product Name: Myo-Inositol, 1,2,3,4,5,6-hexa-O-methyl-
• Synonyms: Myo-Inositol, 1,2,3,4,5,6-hexa-O-methyl-;1-O,2-O,3-O,4-O,5-O,6-O-Hexamethyl-myo-inositol
• CAS NO: 2075-22-1
• Molecular Formula: C12H24O6
• Molecular Weight: 264.31536
• Mol File: 2075-22-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 126 °C(Press: 2 Torr)
• Appearance: /
• Density: 1.06±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Myo-Inositol, 1,2,3,4,5,6-hexa-O-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Myo-Inositol, 1,2,3,4,5,6-hexa-O-methyl-(2075-22-1)
• EPA Substance Registry System: Myo-Inositol, 1,2,3,4,5,6-hexa-O-methyl-(2075-22-1)

Safety Data

• Hazardous Substances Data: 2075-22-1(Hazardous Substances Data)

Upstream product

• 87-89-8 D-myo-inositol 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 

Relevant articles and documents

A novel methylation derivatization method for δ18O analysis of individual carbohydrates by gas chromatography/pyrolysis-isotope ratio mass spectrometry

Rationale The oxygen isotope ratio (δ18O) of carbohydrates derived from animals, plants, sediments, and soils provides important information about biochemical and physiological processes, past environmental conditions, and geographical origins, which are otherwise not available. Nowadays, δ18O analyses are often performed on carbohydrate bulk material, while compound-specific δ18O analyses remain challenging and methods for a wide range of individual carbohydrates are rare. Methods To improve the δ18O analysis of individual carbohydrates by gas chromatography/pyrolysis-isotope ratio mass spectrometry (GC/Pyr-IRMS) we developed a new methylation derivatization method. Carbohydrates were fully methylated within 24 h in an easy-to-handle one-pot reaction in acetonitrile, using silver oxide as proton acceptor, methyl iodide as methyl group carrier, and dimethyl sulfide as catalyst. Results The precision of the method ranged between 0.12 and 1.09‰ for the δ18O values of various individual carbohydrates of different classes (mono-, di-, and trisaccharides, alditols), with an accuracy of a similar order of magnitude, despite high variation in peak areas. Based on the δ18O values of the main isomers, important monosaccharides such as glucose and fructose could also be precisely analyzed for the first time. We tested the method on standard mixtures, honey samples, and leaf carbohydrates extracted from Pinus sylvestris, showing that the method is also applicable to different carbohydrate mixtures. Conclusions The new methylation method shows unrivalled accuracy and precision for δ18O analysis of various individual carbohydrates; it is fast and easy-to-handle, and may therefore find wide-spread application.