2075-46-9 Usage
Uses
Used in Pharmaceutical Synthesis:
4-Nitropyrazole is used as a building block for the synthesis of various pharmaceutical compounds, such as inhibitors and therapeutic agents. Its unique chemical structure allows for the development of highly selective and potent molecules with potential applications in treating various diseases.
Used in Parkinson's Disease Treatment:
4-Nitropyrazole is used as a key component in the synthesis of highly selective, brain-penetrant aminopyrazole LRRK2 Inhibitors. These inhibitors show promise as a potentially viable treatment for Parkinson's disease, as they target the LRRK2 enzyme, which is implicated in the pathology of the condition. By inhibiting this enzyme, 4-Nitropyrazole-based compounds may help slow down the progression of the disease and improve the quality of life for patients.
Check Digit Verification of cas no
The CAS Registry Mumber 2075-46-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,0,7 and 5 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 2075-46:
(6*2)+(5*0)+(4*7)+(3*5)+(2*4)+(1*6)=69
69 % 10 = 9
So 2075-46-9 is a valid CAS Registry Number.
InChI:InChI=1/C3H3N3O2/c7-6(8)3-1-4-5-2-3/h1-2H,(H,4,5)
2075-46-9Relevant academic research and scientific papers
Facile and environmentally friendly synthesis of nitropyrazoles using montmorillonite K-10 impregnated with bismuth nitrate
Ravi,Tewari, Surya P.
experimental part, p. 37 - 41 (2012/04/10)
Nitropyrazoles in higher yields were synthesized using montmorillonite K-10 impregnated with bismuth nitrate and the present procedure may be applied for the nitration of a wide variety of azoles in the drug and pharmaceutical industries.
