2980-33-8Relevant articles and documents
Solvent effect on the alkaline hydrolysis of 2-thiophenyl-3,5- dinitropyridine
Fathalla, Magda F.
, p. 159 - 165 (2006)
The kinetics of the alkaline hydrolysis of 2-thiophenyl-3,5-dinitropyridine were studied spectrophotometrically in different aquo-organic solvents such as methanol, ethanol, n-propyl alcohol, iso-propyl alcohol, t-butyl alcohol, acetonitrile, dimethyl sulfoxide, dioxane, and acetone at 30°C with various solvent compositions up to 80% (v/v) of organic components, An increase in the organic solvent percentage (v/v) has different effects on the reaction rate constants presumably due to hydrogen bond donor HBD and acceptor HBA of the medium and other solvatochromic parameters. Linear and nonlinear plots of log k against the reciprocal of the dielectric constant of the solvent were obtained. The effects are too complex to be analyzed in terms of a single parameter, but an approach using the Kamlet-Taft solvatochromic parameters is applied successfullylo six mixed aquo-organic solvent systems.
Amino- and hydroxymethylation of hydride adducts of 2-hydroxy-3,5- dinitropyridine
Ivanova,Fedyanin,Surova,Blokhin,Atroshchenko,Shahkeldyan
, p. 1000 - 1008 (2013/10/22)
A series of 1,5-dinitro-3,3-diazabicyclo[3.3.1]nonan-2-one derivatives has been synthesized by Mannich condensation of the hydride adduct of 2-hydroxy-3,5-dinitropyridine with formaldehyde and primary amines. The structure of the obtained compounds was proved by NMR spectroscopy.
Reactivity of heterocyclic compounds in nitration. 8. Nitration of 3-hydroxypyridine and its substituted forms
Falyakhov,Gil'manov,Sharnin,Bol'shakova
, p. 830 - 832 (2007/10/03)
Nitration of 3-hydroxypyridine and its substituted forms has been studied under various conditions. It is shown that, depending on the reaction temperature and the nitrating agent, the end products of the synthesis can be 3-hydroxy-2,6-dinitropyridine or 3-hydroxy-2,4,6-trinitropyridine. The possibility of substitutional nitration of iodine derivatives of 2- and 3-hydroxypyridine is demonstrated. 1999 Kluwer Academic/Plenum Publishers.