20759-40-4

Basic information

• Product Name: Benzenesulfonamide, 3-hydroxy- (9CI)
• Synonyms: Benzenesulfonamide, 3-hydroxy- (9CI);Benzenesulfonamide, 3-hydroxy-;3-hydroxybenzene-1-sulfonaMide;3-hydroxy-benzenesulfonic acid aMide;3-hydroxybenzenesulfonamide
• CAS NO: 20759-40-4
• Molecular Formula: C₆H₇NO₃S
• Molecular Weight: 173.18968
• Product Categories: SULFONAMIDE
• Mol File: 20759-40-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 165-166 °C
• Boiling Point: 415.4°C at 760 mmHg
• Flash Point: 205°C
• Appearance: /
• Density: 1.482g/cm³
• Vapor Pressure: 1.72E-07mmHg at 25°C
• Refractive Index: 1.614
• PKA: 8.86±0.10(Predicted)
• CAS DataBase Reference: Benzenesulfonamide, 3-hydroxy- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, 3-hydroxy- (9CI)(20759-40-4)
• EPA Substance Registry System: Benzenesulfonamide, 3-hydroxy- (9CI)(20759-40-4)

Safety Data

• Hazardous Substances Data: 20759-40-4(Hazardous Substances Data)

Usage

General Description

Benzenesulfonamide, 3-hydroxy- (9CI) is a chemical compound that belongs to the class of sulfonamides. It is also known as 3-hydroxybenzenesulfonamide and has the chemical formula C6H7NO3S. Benzenesulfonamide, 3-hydroxy- (9CI) is used in the synthesis of various pharmaceuticals and agrochemicals, particularly as a building block in organic chemistry. It may also have potential applications in the field of medicinal chemistry and drug discovery due to its structure and properties. Additionally, it is important to handle this chemical with caution and follow proper safety protocols when working with it in a laboratory or industrial setting.

InChI:InChI=1/C6H7NO3S/c7-11(9,10)6-3-1-2-5(8)4-6/h1-4,8H,(H2,7,9,10)

Upstream product

• 98-18-0 m-aminobenzenesulfonamide 
• 56157-93-8 3-hydroxybenzene-1-sulfonyl chloride 
• 591-20-8 3-Bromophenol 
• 723-46-6 sulfamethoxazole 

Downstream Products

• 1013925-64-8 3-Oct-7-enyloxy-benzenesulfonamide 
• 146533-50-8 4-(benzyloxy)benzenesulfonamide 
• 847229-81-6 2-amino-3-hydroxy-benzenesulfonamide 
• 3588-76-9 4-amino-3-hydroxy-benzenesulfonic acid amide 

Relevant articles and documents

MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF HEART FAILURE AND DISORDERS RELATED THERETO

The present invention relates to compounds of Formula (la) and pharmaceutical compositions thereof that modulate the activity of the beta-3 adrenergic receptor. Compounds of the present invention and pharmaceutical compositions thereof are directed to methods useful in the treatment of a beta-3 adrenergic receptor-mediated disorder, such as, heart failure and related disorders thereto

Insight into sulfamethoxazole degradation, mechanism, and pathways by AgBr-BaMoO4 composite photocatalyst

A composite photocatalyst, AgBr-BaMoO4 was fabricated by two step method; microwave hydrothermal and precipitation-deposition. The as prepared photocatalyst samples were characterized by various techniques. The facet coupling was seen between the (204) plane of BaMoO4 and (200)/(222) planes of AgBr on the basis of XRD/HRTEM analysis. The pharmaceutical pollutant, sulfamethoxazole was adopted to investigate the photocatalytic performances of samples under UV–vis irradiation. The AgBr-BaMoO4 composite degraded the aqueous sulfamethoxazole drug in UV–vis light about 64% within 75 min, which was attributed to efficient separation of photogenerated electron–hole pairs across the interface between Ag/AgBr and BaMoO4. The multi-electron induced oxygen reduced reaction (ORR) was observed. The radical trapping experiment indicates that OH? has major role for sulfamethoxazole degradation. The four successive photodegradation of sulfamethoxazole in UV–vis light indicates the stability of composite photocatalyst. Furthermore, the three different degradation pathways were designed on the basis of retention time and molecular masses of 18 degraded organic fragments that was confirmed by high-performance liquid chromatography photodiode array (HPLC-PDA) and high resolution-quadruple time of flight electrospray ionization mass spectroscopy (HR-QTOF ESI/MS) techniques. The total organic carbon (TOC) analysis suggested the mineralization of SMZ by composite photocatalyst. This study not only demonstrates the enhancement of photocatalytic performance of wide band gap semiconductor by making composite with narrow band gap semiconductor but also detail degradation pathways and mechanisms of sulfamethoxazole.