207690-49-1Relevant academic research and scientific papers
The Use of Heterocycles for the Conformational Restriction of Biologically Active Peptoids
Horwell, David C.,Lewthwaite, Russell A.,Pritchard, Martyn C.,Ratcliffe, Giles S.,Rubin, J. Ronald
, p. 4591 - 4606 (1998)
A series of piperazinone ring systems have been synthesized as a means of evaluating the effect of conformational restriction of high affinity non-peptide NK1, NK3 and CCK-B receptor ligands.The synthesis of the targeted heterocycles is described along with a discussion of their affinities for their respective receptor types.
